Title

Translational Research

A key aim of the Department of Oncology is the optimal translation of fundamental research into patient benefit. Precision cancer medicine brings together the concepts of biological selection of therapy with anatomical and functional targeting of treatment to deliver the best possible outcomes for a patient with cancer.

Areas of clinical research build on the themes of DNA Damage and Repair and the Tumour Microenvironment and also cover biomarker studies, imaging and clinical trials. Computational biology sits at the interface between genomics, biomarkers and imaging and generates essential knowledge in the pathway to providing cutting-edge clinical treatment for cancer patients. 

Cancer Therapeutics and mRNA Dysregulation

Investigating post-transcriptional mechanisms that drive cancer behaviour and researching novel...

 
Cancer and Immunogenetics Laboratory

Our major interests are in the fundamental genetics and biology of colorectal cancer and their...

 
Oncological Image Analysis

We develop image analysis methods for quantitative analysis of medical images,...

 
Computational Biology and Integrative Genomics

We search for integrated genomic blueprints that enable us to predict how cancer will evolve and...

 
Novel Clinical Imaging Research Group

Our group focuses on using imaging techniques in small-scale trials with the particular...

 
New Technical Radiotherapy/Advanced Radiation Oncology Group

Personalising gastro-intestinal cancers radiotherapy: the ultimate aim of the research of my...

 
Tumour Radiosensitivity Research Group

Our research focuses on finding new ways of making tumours more sensitive to radiotherapy...

 
Adjuvant Colorectal Cancer Group

Delivering the right treatment to the right patient at the right time.

 
DNA Repair in Cancer Treatment Group

We are investigating DNA damage signalling and repair factors in bladder cancer to develop new...

 
IGF Group

We are studying the role of insulin-like growth factor (IGF) signalling in tumour biology,...

 
Clinical Research Programmes, CRUK/MRC Oxford Institute for Radiation Oncology

We aim to deliver a step change in the effectiveness of radiotherapy through the evaluation of...

 
Early Phase Clinical Trials & Melanoma Therapy

Mark Middleton’s research concentrates on development of new cancer drugs and on the treatment...

 
Oxford Molecular Diagnostics Centre

The aim of our research is to identify molecular-based disease classifiers using clinical omics...

 
Experimental Radiation Therapeutics Group

Personalising radiotherapy using functional imaging: we apply functional and molecular imaging...

 
Radiation Therapy Medical Physics Group

Our research group specialises in bringing fundamental physical concepts to enhance everyday...

 
Advanced Technology Development Group

Our work focuses on the application of novel imaging modalities and on the development of...

 
About Us
We aim to enhance clinical and basic cancer research in Oxford with the ultimate goal of increasing cancer cure rates.
Research
In Oxford, we have a great wealth of broad-ranging expertise and a powerful network of cancer researchers.
Study With Us
Our graduate training programmes for both scientists and clinicians are internationally recognised.