Sponsor: University of Oxford & North West London Hospitals NHS Trust
Funded by: Cancer Research UK, Bobby Moore Fund www.cancerresearchuk.org
Conventional versus laparoscopic surgery for colorectal cancer within an enhanced programme.
The aim of the trial is to compare two different approaches to surgery for bowel cancer, within an enhanced recovery programme.
Closed to recruitment.
Target recruitment: 202
Total recruitment: 204 patients (May 2012)
Active sites: 11 (May 2012)
- Diagnosis of colorectal cancer
- Suitable for elective resection following planned admission
- >= 18 years of age
- Written informed consent given
- Acute intestinal obstruction
- Unplanned admission to hospital
- Unsuitability for epidural insertion - determined pre-randomisation
- Unsuitable for laparoscopic resection as conversion to open surgery is likely
- Post-operative physical fatigue
- Post-operative stay
- 30 day and in-hospital complications
- 30 day re-admission & re-operation rates
- Assessment of health economics using cost-effectiveness & cost utility
- Patient reported and functional outcomes
- Cosmetic assessments
EnROL is the first trial run by OCTO that is using web-based submission of data (eCRFs) including randomisation.
Recruitment started: July 2008
End of Recruitment: 18 May 2012
End of Trial: 30 June 2015