X-rays can trigger the FLASH effect: Ultra-high dose-rate synchrotron light source prevents normal brain injury after whole brain irradiation in mice.
Montay-Gruel P., Bouchet A., Jaccard M., Patin D., Serduc R., Aim W., Petersson K., Petit B., Bailat C., Bourhis J., Bräuer-Krisch E., Vozenin M-C.
This study is the first proof of concept that the FLASH effect can be triggered by X-rays. Our results show that a 10 Gy whole-brain irradiation delivered at ultra-high dose-rate with synchrotron generated X-rays does not induce memory deficit; it reduces hippocampal cell-division impairment and induces less reactive astrogliosis.