Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

In response to DNA damage, E2F-1 is induced and phosphorylated. Phosphorylated E2F-1 can reside in discrete nuclear structures and induce apoptosis, suggesting a unique role for E2F-1 in DNA repair and checkpoint functions.

Type

Journal article

Journal

Cell Cycle

Publication Date

09/2003

Volume

2

Pages

435 - 437

Keywords

Animals, Apoptosis, Cell Cycle, Cell Cycle Proteins, Cell Nucleus, DNA Damage, DNA Repair, DNA-Binding Proteins, E2F Transcription Factors, E2F1 Transcription Factor, Humans, Mitogen-Activated Protein Kinases, Phosphorylation, Signal Transduction, Transcription Factors, Tumor Suppressor Protein p53