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Radionuclide spatial distribution and dose deposition for in vitro assessments of 212 Pb-αVCAM-1 targeted alpha therapy.
PURPOSE: Targeted alpha therapy (TAT) takes advantage of the short-range and high linear-energy-transfer of α-particles and is increasingly used, especially ...
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Influence of pH on the conformation and stability of mismatch base-pairs in DNA.
A series of self-complementary dodecanucleotide duplexes containing two symmetrically disposed mismatches have been studied by pH-dependent, ultraviolet light ...
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Missense mutations in the arylsulphatase A genes of metachromatic leukodystrophy patients.
Novel predicted disease-causing mutations have been defined in three patients with metachromatic leukodystrophy (MLD). The first new mutation is a C-->A change ...
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Characterisation of the changing genomic landscape of metastatic melanoma using cell free DNA.
Cancer is characterised by complex somatically acquired genetic aberrations that manifest as intra-tumour and inter-tumour genetic heterogeneity and can lead ...
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Serological identification of Ia antigens: report of a British region Ia workshop.
In preparation for the 7th International Histocompatibility Workshop 13 laboratories in the British Region participated in a local workshop. One hundred and ...