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APC mutation associated with late onset of familial adenomatous polyposis.
Familial adenomatous polyposis is an autosomal dominantly inherited disorder. Mutation studies in the corresponding gene (APC) may provide information for ...
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Phenotypic expression in familial adenomatous polyposis: partial prediction by mutation analysis.
The phenotypic expression in familial adenomatous polyposis (FAP) is variable. This study compares the phenotype of 27 patients with an identical 5 base pair ...
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Systematic identification of trans eQTLs as putative drivers of known disease associations.
Identifying the downstream effects of disease-associated SNPs is challenging. To help overcome this problem, we performed expression quantitative trait locus ...
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The HABP2 G534E variant is an unlikely cause of familial non-medullary thyroid cancer.
CONTEXT: A recent study reported the non-synonymous G534E (rs7080536, allele A) variant in the HABP2 gene as causal in familial non-medullary thyroid cancer ...
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Comparison of molecular strategies for breast cancer virotherapy using oncolytic adenovirus.
Oncolytic viruses are regulated by the tumor phenotype to replicate and lyse cancer cells selectively. To identify optimal strategies for breast cancer we ...