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Neuroprotection by dimethyloxalylglycine following permanent and transient focal cerebral ischemia in rats
Dimethyloxalylglycine (DMOG) is an inhibitor of prolyl-4-hydroxylase domain (PHD) enzymes that regulate the stability of hypoxia-inducible factor (HIF). We ...
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Neuroprotection by dimethyloxalylglycine following permanent and transient focal cerebral ischemia in rats.
Dimethyloxalylglycine (DMOG) is an inhibitor of prolyl-4-hydroxylase domain (PHD) enzymes that regulate the stability of hypoxia-inducible factor (HIF). We ...
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Epidermal-growth-factor receptors in human bladder cancer: comparison of invasive and superficial tumours.
The presence of epidermal-growth-factor (EGF) receptors in normal and neoplastic human urothelium was studied in 12 control patients and in 48 patients with ...
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100km non-stop in 24 hours
Five members of Professor Len Seymour's laboratory (Arthur Dyer, Sally Frost, Sophie Owen, Tzveta Pokrovska and Ellie Scott) are limbering up to walk 100km ...
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Participation of DNA-PKcs in DSB repair after exposure to high- and low-LET radiation.
Cellular lesions (e.g. DSBs) are induced into DNA upon exposure to radiation, with DSB complexity increasing with radiation ionization density. Using M059K and ...