Our goals are to identify the role of the inflammatory and metabolic microenvironment in brain metastasis, and to develop imaging biomarkers for tumour detection and monitoring.
The aim of our research is to design and develop innovative cancer killing viruses and oncolytic vaccines.
Our research links basic science with clinical applications and focuses on understanding the mechanisms behind tumour resistance to radiation.
Our research aims to understand the cell and molecular biology behind frequent tumour mutations and how they influence cancer onset and/or therapy.
We aim to develop new radioisotope-labelled compounds for the imaging of tumour biology.
Sponsor: University of Oxford
ClinicalTrials.gov Number: NCT02024009
EudraCT number: 2013-004968-56
Systemic therapy and Chemoradiation in Advanced LOcalised Pancreatic cancer – 2
Full title: A multi-centre randomised study of induction chemotherapy followed by capecitabine (+/- nelfinavir) with high or standard dose radiotherapy for locally advanced non-metastatic pancreatic cancer
Our group aims to identify novel therapies that target subgroups of lung cancer patients harbouring specific genetic changes.
The focus of the group is on tumour angiogenesis and the role of notch signalling, and hypoxia biology and its regulation.
Investigating post-transcriptional mechanisms that drive cancer behaviour and researching novel cancer therapeutics for patients with advanced malignancies.
We are studying the role of insulin-like growth factor (IGF) signalling in tumour biology, aiming to use this information to develop new ways to prevent and treat cancer.