COVID-19 in children with haematological malignancies.
Millen GC., Arnold R., Cazier J-B., Curley H., Feltbower R., Gamble A., Glaser A., Grundy RG., Kirton L., Lee LYW., McCabe MG., Palles C., Phillips B., Stiller CA., Varnai C., Kearns P.
BACKGROUND: Children with cancer are not at increased risk of severe SARS-CoV-2 infection; however, adults with haematological malignancies have increased risk of severe infections compared with non-haematological malignancies. METHODS: We compared patients with haematological and non-haematological malignancies enrolled in the UK Paediatric Coronavirus Cancer Monitoring Project between 12 March 2020 and 16 February 2021. Children who received stem cell transplantation were excluded. RESULTS: Only 2/62 patients with haematological malignancy had severe/critical infections, with an OR of 0.5 for patients with haematological compared with non-haematological malignancies. INTERPRETATION: Children with haematological malignancies are at no greater risk of severe SARS-CoV-2 infection than those with non-haematological malignancies.