A SARS-Cov-2 sensor based on upconversion nanoparticles and graphene oxide.
Alexaki K., Kyriazi ME., Greening J., Taemaitree L., El-Sagheer AH., Brown T., Zhang X., Muskens OL., Kanaras AG.
Since the beginning of the COVID-19 pandemic, there has been an increased need for the development of novel diagnostic solutions that can accurately and rapidly detect SARS-CoV-2 infection. In this work, we demonstrate the targeting of viral oligonucleotide markers within minutes without the requirement of a polymerase chain reaction (PCR) amplification step via the use of oligonucleotide-coated upconversion nanoparticles (UCNPs) and graphene oxide (GO).