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The heterocyclic base 7-aminopropargyl-7-deaza-2,6-diaminopurine (D) has been incorporated into oligodeoxynucleotides. D:T has similar thermodynamic stability to G:C and is a stable analogue of A:T.

Original publication

DOI

10.1039/b409155h

Type

Journal article

Journal

Chem Commun (Camb)

Publication Date

07/10/2004

Pages

2208 - 2209

Keywords

Adenine, Base Pairing, Base Sequence, Cytosine, Guanine, Nucleic Acid Conformation, Thermodynamics, Thymine