Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

The synthesis of 1-deazacytidine, the C-nucleoside analogue of cytidine, is described. It involves coupling of a protected 2-amino-5-bromopyridine with perbenzylated ribonolactone and transformation of the pyridine ring into the desired substituted pyridone. This synthesis completes the family of C-nucleosidic analogues of natural nucleosides. © 2002 Elsevier Science Ltd. All rights reserved.

Original publication

DOI

10.1016/S0040-4039(02)00481-1

Type

Journal article

Journal

Tetrahedron Letters

Publication Date

22/04/2002

Volume

43

Pages

3121 - 3123