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Molecular radiotherapy (MRT) has been used clinically for around 75 years. Despite this long history of clinical use, there is no established dosimetry practice for calculating the absorbed dose delivered to tumour targets or to organs at risk. As a result, treatment protocols have often evolved based on experience with relatively small numbers of patients, each receiving a similar administered activity but, potentially, widely varying doses. This is in stark contrast to modern external-beam radiotherapy practice. This commentary describes some of the barriers to MRT dosimetry and gives some opinions on the way forward.

Original publication

DOI

10.1259/bjr.20140720

Type

Journal article

Journal

Br J Radiol

Publication Date

03/2015

Volume

88

Keywords

Clinical Protocols, Humans, Neoplasms, Radiometry, Radiotherapy Dosage, Time Factors