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The Oncology Clinical Trials Office (OCTO) provides clinical trial management support to investigators across the CRUK Oxford Centre to manage trials from concept to completion.

 OCTO was established in 2002 to run trials concerned with the practical application of high quality research into innovative and effective cancer therapies. We aim to become the leading centre for translational early phase oncology trials in the UK.

We can provide support for protocol development, funding applications, ethics and regulatory approvals, study site selection and management, IMP and trial supplies, monitoring, data management including eCRFs, and pharmacoviglance / safety reporting.

We work with investigators to develop and deliver trials in medical oncology, radiotherapy and imaging from first-in-human CTIMPs to large clinical studies across a range of tumour types.  We have particular expertise in delivering early phase multi-centre trials for biologically distinct populations. By working with over 250 study sites (hospitals) and collaborating academic groups in the UK, Europe, USA and Australia we have recruited over 10,000 patients into trials.

 If you would like to know more please send all enquiries to