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New trial of personalised cancer treatment begins in Oxford

The first human trial of a pioneering personalised cancer treatment developed at Oxford University will begin this week, with the potential to tackle a wide range of late-stage cancers.

A major challenge in drug development is that all cancer patients respond differently to treatment, making it difficult to know how best to treat each patient. For the first time, a phase I trial in Oxford will investigate not only a new drug, called CXD101, but also a new test to predict which patients could be successfully treated by this class of drug.

Major EPSRC Programme Grant to Support New Oxford Centre for Drug Delivery Devices

Cancer therapy drugs tend to achieve limited accumulation and poor penetration in tumours, reducing their effectiveness. For many years, the only methods used to improve drug uptake by tumours have been pharmacological, and these have had limited success.

Recent research at Oxford University has shown that physical mechanisms triggered by ultrasound, magnetic fields or shock waves can dramatically improve the delivery and penetration of existing and experimental drugs into tumours.

Professor Gillies McKenna Receives Gold Medal

Professor Gillies McKenna, Head of the Department of Oncology, has been awarded the Gold Medal by the Royal College of Radiologists in recognition of the outstanding contribution that he has made to the field of radiation oncology.

At the award ceremony, held in London in November 2014, Professor McKenna also delivered the twelfth David Skeggs lecture, entitled Imaging and Targets: The Molecular Frontiers in Radiation Oncology.

Oxford Medical Sciences excels in REF 2014 exercise

Today’s Research Excellence Framework (REF 2014) results confirm the University of Oxford’s world leading position in medical sciences research.

Furthermore, the University overall has the largest volume of world leading research and impact submitted to the REF exercise.

The Department of Oncology is part of the Medical Sciences Division and submitted under Clinical Medicine, a unit of assessment in which we ranked top for overall quality.

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