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Walter BodmeR

1. Bispecific monoclonal antibodies for cancer immunotherapy

2. Differentiation in colorectal cancer


Andrew Blackford

Investigating how cells repair DNA damage during mitosis


Francesca Buffa

Combining CRISPR and RNAseq to dissect molecular circuits in a hypoxic tumour microenvironment


David Clynes

Targeting telomere maintenance and repair in cancer


Vincenzio D'Angiolella

Ubiquitin signalling in the pathogenesis and therapy of glioblastoma


Amato Giaccia

The role of the AXL Receptor Tyrosine Kinase in the DNA damage response


Ester Hammond

1. Hypoxia links the unfolded proteim response with the DNA damage response.
2. Investigation of the contribution of redox stress to the therapy resistance of cells experiencing cycling oxygen levels
3. Understanding the impact of hypoxia dynamics on therapeutic response in breast cancer


Geoffrey Higgins

Pre-clinical investigations of POLQ inhibitors


Tim Humphrey

DNA repair fidelity, radiosensitivity and cancer

Shisong Jiang

1. Cross presentation of antigens of recombinant overlapping peptides to optimise vaccines against tumour and infectious diseases
2. Autoimmunity against TNF and its role in inflammatory diseases


Nick La Thangue

Translating epigenetic control into novel cancer therapeutics


Valentine Macaulay

Investigating IGF-1 as a cancer risk factor


Peter McHugh

Targeting DNA repair to overcome cancer therapy resistance

Eileen Parkes

Inflammation in the tumour microenvironment

Kristijan Ramadan

Characterisation of DNA-protein crosslink proteolysis repair in cancer and therapy


Len Seymour

Exosomes in oncolytic virotherapy


Katherine Vallis

1. Strategies to enhance efficacy of nucleotide therapeutics for targeted cancer therapy
2. Early detection of oesophageal cancer


Frank Van Den Heuvel

MROnics used in MR Linac applications