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You will undertake a research placement leading to a dissertation. This is a substantial piece of work and accounts for 60% of the total marks awarded for the MSc degree. This will provide you with experience of working in an active research laboratory contributing to the research of the group and, potentially, publications. The purpose of the dissertation and subsequent viva is to ensure that you have a good understanding of research practice and study design. You will be assessed on your academic ability, critical thinking, originality and  your understanding of the pragmatics of research.

A list of dissertation projects and potential supervisors will be provided in Michaelmas term (December), but you are encouraged to explore project opportunities during the first term.

The research project element of the course covers a wide range of topics. While the majority of projects are undertaken within the Department, projects have also been undertaken within other Oxford Departments and external Institutions. Projects which have previously been offered:

  • Targeting Tumour Hypoxia to improve Radiotherapy Outcome
  • Ubiquitin signalling in the pathogenesis and treatment of glioblastoma
  • Imaging DNA damage repair of neuroendocrine tumours during radionuclide therapy
  • Modelling Disrupted Transcriptomic Networks in Hypoxic Tumours
  • Mechanisms linking transcriptional control of the circadian clock and radiation-induced leukaemia
  • Adaptive radiotherapy for rectal cancer - what are the benefits?
  • The role of SPRTN (SPARTAN) in genome stability, ageing and cancer
  • Macrophages and the Radiation Response
  • A search for a gene signature predictive of radiation response in multiple cancer types
  • Selective modulation of tumour extracellular pH using glucose measured by amide transfer magnetic resonance imaging
  • Radiation, diet and hypoxia: Investigating the potential of a ketogenic diet to improve radiotherapy response
  • Exploiting the immune system via IL-6 as a radiosensitising mechanism in bladder cancer
  • Application of a Compartmental Model to I-131 Therapy Dosimetry
  • High LET radiation effects related to protection for the lens of the eye
  • Dosimetric differences between margin-based and ribust optimisation VMAT plans in NSCLC