BSc, MSc, PhD
Alessandro graduated from University of Pavia (Italy) in Computer Science Engineering with a Thesis focusing on the identification of an order parameter in Monte Carlo simulations of dipolar systems on hexagonal lattices.
After completing his Master’s Degree, Alessandro started a PhD in Electronics, Computer Science and Electrical Engineering within the Custom Computing and Programmable Systems group at the same University. During his PhD, he specialised in High Performance Computing and Data Processing. In particular, he focused on Graphics Processing Units (GPUs) and Field Programmable Gate Arrays (FPGAs) technologies to develop real time solutions for image analysis. His main project was in collaboration with Professor Antonio Plaza, Head of the Hyperspectral Computing Laboratory, University of Extremadura.
Biomarkers of diagnosis, prognosis and response to treatment are essential for delivering personalised healthcare. An unprecedented technological development in molecular research has recently boosted biomarker discovery, and enabled the acquisition and storage of an increasing volume of molecular and genomic data in large clinical cohorts. Alessandro’s main research activity is related to the development of computational methods to exploit such data for the identification of new biomarkers.
Guidelines for using sigQC for systematic evaluation of gene signatures.
Dhawan A. et al, (2019), Nat Protoc, 14, 1377 - 1400
Serum microRNA expression during neoadjuvant chemoradiation for rectal cancer.
Lim SH-S. et al, (2017), JOURNAL OF CLINICAL ONCOLOGY, 35
SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development.
Raducu M. et al, (2016), EMBO J, 35, 1400 - 1416
Paracrine effect of GTP cyclohydrolase and angiopoietin-1 interaction in stromal fibroblasts on tumor Tie2 activation and breast cancer growth.
Chen L. et al, (2016), Oncotarget, 7, 9353 - 9367
Real-time implementation of the vertex component analysis algorithm on GPUs
Barberis A. et al, (2013), IEEE Geoscience and Remote Sensing Letters, 10, 251 - 255