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Gillies McKenna
Professor of Radiation Oncology and Biology
Research Summary
Our research links basic science with clinical applications and focuses on understanding the mechanisms behind tumour resistance to radiation.
Biography
Gillies McKenna was Director of the Oxford Institute for Radiation Oncology from 2005 to 2019, and Head of the Department of Oncology at the University of Oxford since its formation in 2010 to March 2017.
Prior to that, he was Chairman and Henry K. Pancoast Associate Professor of Radiation Oncology at the University of Pennsylvania School of Medicine, rising to Professor in 1995.
He has received several awards and honours including the Weiss Medal from the Association for Radiation Research, the Frank Ellis Medal from the Royal College of Radiologists, the Roentgen Medal from the Deutches Roentgen Museum and the Gold Medal from the Royal College of Radiologists.
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Recent publications
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Safety and tumour hypoxia modifying effect of buparlisib with radiotherapy in NSCLC: a phase I dose escalation study
Conference paper
McGowan DR. et al, (2018)
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Nucleoporin 54 contributes to homologous recombination repair and post-replicative DNA integrity.
Journal article
Rodriguez-Berriguete G. et al, (2018), Nucleic Acids Res, 46, 7731 - 7746
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Oxidative Phosphorylation as an Emerging Target in Cancer Therapy.
Journal article
Ashton TM. et al, (2018), Clin Cancer Res, 24, 2482 - 2490
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STING-Dependent Interferon-λ1 Induction in HT29 Cells, a Human Colorectal Cancer Cell Line, After Gamma-Radiation.
Journal article
Chen J. et al, (2018), Int J Radiat Oncol Biol Phys, 101, 97 - 106
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CDK1 inhibition sensitizes normal cells to DNA damage in a cell cycle dependent manner.
Journal article
Prevo R. et al, (2018), Cell Cycle, 17, 1513 - 1523