Junetha Syed Jabarulla
BSc, MSc, PhD
DNA damage repair and radiosensitization
Junetha graduated from Madurai Kamaraj University (India) in Microbial gene Technology. Following her Master’s she joined as a Project Associate in the Department of Biotechnology, Indian Institute of Technology Madras working on the Functional characterization of Ras association domain-containing proteins. In 2012, she started her PhD in Chemical Biology with Prof. Hiroshi Sugiyama, Kyoto University, Japan. Her PhD thesis focused on regulating the eukaryotic gene expression by programmable DNA-binding small molecules Pyrrole-imidazole polyamides. After completing her PhD, she joined University of Warwick, UK in 2016 as a Post-Doctoral Researcher working on the genetic code expansion in Zebrafish embryos. In 2018, Junetha started as a Post-Doctoral researcher in the DNA Repair in Cancer Treatment group, Department of Oncology, University of Oxford.
I am investigating the acetylation dynamics of non-histone proteins particularly DNA repair proteins following HDAC inhibition and elucidating the biological significance of this post translational modification with respect to radiosensitisation.
Expanding the zebrafish genetic code through site-specific introduction of azido-lysine, bicyclononyne-lysine, and diazirine-lysine
Syed J. et al, (2019), International Journal of Molecular Sciences, 20
RNA-DNA Triplex Formation by Long Noncoding RNAs
Li Y. et al, (2016), Cell Chemical Biology, 23, 1325 - 1333
Genome-Wide Assessment of the Binding Effects of Artificial Transcriptional Activators by High-Throughput Sequencing
Chandran A. et al, (2016), ChemBioChem, 17, 1905 - 1910
Deciphering the genomic targets of alkylating polyamide conjugates using high-throughput sequencing
Chandran A. et al, (2016), Nucleic Acids Research, 44, 4014 - 4024
Effect of ATRX and G-Quadruplex Formation by the VNTR Sequence on α-Globin Gene Expression
Li Y. et al, (2016), ChemBioChem, 17, 928 - 935