Colleges
Kay Shigemori
Postdoctoral Researcher
Biography
Kay Shigemori joined the Department of Oncology as a DPhil student from 2018. Prior to arriving at Oxford, she did her Bachelors degree in Biology at Colby College in Maine, USA. After completing her undergraduate studies, she worked as a research assistant in the Weinstock laboratory at the Dana-Farber Cancer Institute (DFCI) in Boston. During her time at DFCI, she contributed to several translational research projects and led the patient-derived leukemia and lymphoma xenografts effort.
Kay is currently studying the role of the immune microenvironment in lung cancer development. Her study looks at the involvement of innate immunity, such as the virally-induced cGAS-STING pathway in the process of lung tumour development.
She is a recipient of the National Cancer Research Institute Award in 2020.
Radiation and DMXAA limit tumour development in a urethane-induced lung cancer model through inflammatory response.
Collaborators
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Eileen Parkes
Associate Professor, Innate tumour immunology
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Alistair Easton
Senior Clinical Researcher
Recent publications
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Olaparib increases the therapeutic index of hemithoracic irradiation compared with hemithoracic irradiation alone in a mouse lung cancer model.
Journal article
Jiang Y. et al, (2021), Br J Cancer, 124, 1809 - 1819
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Genomic landscape of young ATLL patients identifies frequent targetable CD28 fusions.
Journal article
Yoshida N. et al, (2020), Blood, 135, 1467 - 1471
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Identification of Circulating Serum Multi-MicroRNA Signatures in Human DLBCL Models
Journal article
Beheshti A. et al, (2019), Scientific Reports, 9
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Genomic Landscape of Young ATLL Patients Identifies Frequent Targetable CD28 Fusions
Conference paper
Yoshida N. et al, (2019), BLOOD, 134
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Expression of mutant CHMP2B linked to neurodegeneration in humans disrupts circadian rhythms in Drosophila
Journal article
Lee D. et al, (2019), FASEB BioAdvances, 1, 511 - 520