Tumour Microenvironment (Co-Investigator)
Junior Group Leader
Our group objective is to understand the role of the ubiquitin system in cancer cell survival and response to radiation treatment. Further investigation in this process will prove to be a powerful tool for the design and implementation of novel cancer treatments
Vincenzo D’Angiolella is a junior Group Leader at the Oxford Institute for Radiation Oncology. He has a Medical Degree (MD) from the University of Naples “Federico II” and completed his PhD at the same University in the field of General Pathology. Following the completion of his studies, he worked as a postdoctoral fellow at the New York University School of Medicine in the USA in the laboratory of Professor Michele Pagano.
He has been awarded fellowships from AIRC (Associazione Italiana per la Ricerca sul Cancro) and AICF (American Italian Cancer Foundation) and was a Scholar of the Leukemia & Lymphoma Society from 2008 to 2011.
Vincenzo D'Angiolella's Group
Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12
BULLOCK A. et al, (2020), Open Biology
Burdova K. et al, (2019), EMBO J, 38
D'Angiolella V. et al, (2019)
Mavrommati I. et al, (2018), Cell Rep, 24, 3404 - 3412
Fung E. et al, (2018), EMBO Rep, 19