Marie Sklodowska-Curie ITN Early-Stage Researcher

A fellowship position is available for a period of 30 months, tenable at Oxford University Department of Oncology (CRUK/MRC Institute for Radiation Oncology), on a project entitled SYNTRAIN – Targeting SYNthetic lethal interactions for new cancer treatments TRAINing network. The successful candidate will be registered for PhD training while employed by the University on a Marie Sklodowska-Curie Innovative Training Network, and will be expected to work within the laboratory of Genome Stability and Tumourigenesis led by Professor Madalena Tarsounas. The research project is focused on understanding how tumour cells lacking BRCA1 or BRCA2 gene function differ from normal cells in their responses to exogenous damage induced by ionising radiation, as well as to cell-intrinsic challenges that arise during DNA replication. Experimental work will investigate specific targeting of cells and tumours lacking BRCA1 or BRCA2 with chemotherapeutic drugs and/or ionising radiation and is therefore deeply relevant to the search for treatments that would selectively kill tumour cells whose capacity for homologous recombination-mediated repair has been compromised (i.e. lacking BRCA1 or BRCA2 genes). Candidates must possess a good degree (2:1 or equivalent) in a relevant subject, along with the ability to design robust well-controlled experiments, to perform them comprehensively and to interpret the data objectively. You should have experience of appropriate laboratory techniques and a good knowledge of cancer biology literature.
The EC funding for this position provides for a remuneration starting from £28,489 p.a. Actual salary will depend on employer deductions, personal circumstances and the exchange rate applicable to the fellowship. This amount includes an annual living allowance and a mobility allowance (to cover the expenses associated with working in a different country). Under the terms of the EC funding, which aims to promote mobility within the research community, to be eligible for the post you must not have been resident in the UK for more than a total of 12 months in the past 3 years. Persons who have obtained a doctorate or had more than 4 years full time research experience are ineligible.
The start date is subject to discussion; the latest possible date is 1 March 2018.
Further particulars for the post can be found in the job description. This is a full-time post and is funded for 2.5 years.
All applicants must complete an application form and supporting statement.
The closing date for applications is 12.00 noon on 1 December 2017.

Closing Date: 
Friday, December 1, 2017 - 12:00
Organisation: 
CRUK/MRC Oxford Institute for Radiation and Oncology
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