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The 5-year programme award will support research on the DNA repair mechanisms that protect cancer cells from therapy, informing the development of future therapies.

Peter McHugh (right) with Chris Schofield (Department of Chemistry) and Opher Gileadi (Nuffield Department of Medicine)

Liquid biopsy for the diagnosis of EBV-positive Burkitt's lymphoma in endemic areas.

Journal article

Chamba C. et al, (2026), Nat Med

Supplementary Figure S6 from Combined Oxygen-Enhanced MRI and Perfusion Imaging Detect Hypoxia Modification from Banoxantrone and Atovaquone and Track Their Differential Mechanisms of Action

Other

O’Connor JPB. et al, (2026)

Supplementary Figure S2 from Combined Oxygen-Enhanced MRI and Perfusion Imaging Detect Hypoxia Modification from Banoxantrone and Atovaquone and Track Their Differential Mechanisms of Action

Other

O’Connor JPB. et al, (2026)

Supplementary Figure S4 from Combined Oxygen-Enhanced MRI and Perfusion Imaging Detect Hypoxia Modification from Banoxantrone and Atovaquone and Track Their Differential Mechanisms of Action

Other

O’Connor JPB. et al, (2026)

Supplementary Figure S5 from Combined Oxygen-Enhanced MRI and Perfusion Imaging Detect Hypoxia Modification from Banoxantrone and Atovaquone and Track Their Differential Mechanisms of Action

Other

O’Connor JPB. et al, (2026)

Supplementary Figure S1 from Combined Oxygen-Enhanced MRI and Perfusion Imaging Detect Hypoxia Modification from Banoxantrone and Atovaquone and Track Their Differential Mechanisms of Action

Other

O’Connor JPB. et al, (2026)

Supplementary Figure S3 from Combined Oxygen-Enhanced MRI and Perfusion Imaging Detect Hypoxia Modification from Banoxantrone and Atovaquone and Track Their Differential Mechanisms of Action

Other

O’Connor JPB. et al, (2026)

Data from Combined Oxygen-Enhanced MRI and Perfusion Imaging Detect Hypoxia Modification from Banoxantrone and Atovaquone and Track Their Differential Mechanisms of Action

Other

O’Connor JPB. et al, (2026)

HIF-1-regulated TPM3 links hypoxia to motility and invasion beyond the hypoxic fraction in triple-negative breast cancer.

Journal article

Zhou C. et al, (2026), NPJ Breast Cancer

Chromosomal instability shapes the tumor microenvironment of esophageal adenocarcinoma via a cGAS-chemokine-myeloid axis.

Journal article

Beernaert B. et al, (2026), Sci Adv, 12

Lipid-rich ascites reprograms T cell lipid metabolic transcriptome to drive dysfunction

Preprint

Wan PK-T. et al, (2026)

High-risk molecular features may eclipse genomic complexity in predicting chronic lymphocytic leukemia outcomes; UK clinical trial insights.

Journal article

Parker H. et al, (2026), Leukemia

The vital role of p97/valosin-containing protein-mediated degradation pathways in tumour immunity.

Journal article

Phyu SM. et al, (2026), Curr Opin Cell Biol, 99

A hierarchy of causes of death in senescent C. elegans

Journal article

Wang H. et al, (2026), npj Aging

ISDE guidelines on the management of cT2N0 esophageal cancer.

Journal article

Kohn GP. et al, (2026), Dis Esophagus, 39

Fully automated volumetry of ventricular subregions on computed tomography using object detection and semantic segmentation.

Journal article

Da Mutten R. et al, (2026), Neuroimage Rep, 6

The OligoPanc project: an interdisciplinary expert consensus statement on oligometastatic pancreatic cancer.

Journal article

Leonhardt C-S. et al, (2026), Lancet Oncol, 27, e141 - e149

Photon FLASH spares radiation-induced changes in cardiac function, remodelling and arrythmia in a preclinical model.

Journal article

Ghita-Pettigrew M. et al, (2026), Radiother Oncol, 216

HLA Heterozygosity Influences Colorectal Cancer Risk and Survival Outcome.

Journal article

Tsai Y-Y. et al, (2026), Gastroenterology, 170, 619 - 622

DESTINY-Gastric05 phase III trial of first-line trastuzumab deruxtecan, chemotherapy, and pembrolizumab in HER2-positive gastric or gastroesophageal junction cancer

Journal article

Janjigian YY. et al, (2026), ESMO Gastrointestinal Oncology, 11

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