Graphene integrated optical biosensor for detection of breast cancer cell media
Sun J., Jiang H., Coutts AS., Zhu W., Hunt J., Chen X.
We report a graphene oxide integrated optical biosensor for the detection of breast cancer cell media. The graphene oxide nanosheets-coated long period grating (GO-LPG) serves as an optical transducer where the GO acts as a bridging interface between optical sensor and external medium. The principle of the optical biosensor is based on alerting the optical signal as a change of local refractive index caused by different analyte concentrations. The proposed biosensor has been implemented to detect the breast cancer cell media with ultrahigh sensitivity, opening the path as a bio-nano-photonic platform for biosensing and early diagnosis.