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Hybridomas secreting monoclonal antibodies against herpes simplex virus (HSV) DNA binding proteins (DBP) have been produced. Five HSV DBP have been characterized according to molecular weight, affinity for DNA, kinetic class and localization within the infected cell. By preparing an immunoadsorbent column from antibody TI8, its specific DBP was purified to apparent homogeneity. The purified DBP retained the ability to bind to DNA. © 1984 Springer-Verlag.

Original publication

DOI

10.1007/BF01314300

Type

Journal article

Journal

Archives of Virology

Publication Date

01/03/1984

Volume

79

Pages

13 - 33