Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Angiogenesis inhibitors cause increased hypoxia in tumors and this results in the induction of cytoprotective autophagy. Targeting this adaptation using autophagy inhibitors can overcome resistance to antiangiogenic therapy and enhance the antitumor effects.

Original publication

DOI

10.1158/1078-0432.CCR-13-0634

Type

Journal article

Journal

Clin Cancer Res

Publication Date

01/06/2013

Volume

19

Pages

2791 - 2793

Keywords

Angiogenesis Inhibitors, Animals, Antineoplastic Agents, Autophagy, Colonic Neoplasms, Female, Humans