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The capacity of platelets, lymphocytes, leukocytes (mixed lymphocytes and granulocytes) and erythrocytes to absorb 12 leukocyte agglutinins from multiparous women was investigated. Erythrocytes did not absorb these agglutinins. Platelets, lymphocytes and granulocytes appeared to share antigens identified by representative antisera belonging to the Group 4 and the LA antigen systems. Leukocyte antisera specific for a single blood cell line were not encountered. Approximately 20 times as many platelets as lymphocytes or leukocytes were required to absorb an aliquot of serum. The quantities necessary for absorption indicate that whole blood is an inefficient source of antigen for large scale production of monospecific from multi‐specific leukocyte antisera. 1966 AABB

Original publication

DOI

10.1111/j.1537-2995.1966.tb04724.x

Type

Journal article

Journal

Transfusion

Publication Date

01/01/1966

Volume

6

Pages

193 - 204