Department of Oncology

Real-world obesity prevalence and history in 79 271 patients receiving systemic anticancer therapy across 13 cancer types in England (2013-2023).

Perletta V. et al, (2026), ESMO Real World Data Digit Oncol, 12

PHGDH loss promotes hypoxia tolerance through glycolytic reprogramming and enhanced HIF-1 activity

Petrosyan E. et al, (2026), Cell Death Discovery

Transforming perioperative treatment of gastro-oesophageal adenocarcinoma: triumphs, setbacks and future horizons.

Zhu H. et al, (2026), Nat Rev Clin Oncol

Bivalent virus-like particles expressing SPECT1 and CSP trigger pre-erythrocytic malaria immunity and protect against transgenic Plasmodium falciparum sporozoite challenge in mice

Turan G. et al, (2026), Frontiers in Immunology, 17

Catalog of gut microbiota alterations associated with anticancer therapies across multiple cancer types

Kurihara K. et al, (2026)

Germline haploinsufficiency of MUTYH causes mutational signature SBS18 in multiple tumour types and specifically raises colorectal cancer risk.

Sherwood K. et al, (2026), NPJ Precis Oncol

Mitigating algorithmic unfairness arising from forgetfulness of medical records in clinical artificial intelligence.

Chen Y. et al, (2026), Nat Commun

Hedgehog Inhibitor and Paclitaxel: A Phase I Trial of the Oral Hedgehog inhibitor Taladegib in Combination with Weekly Paclitaxel in Patients with Advanced Solid Tumours.

Glasspool R. et al, (2026), Invest New Drugs

The PRAGMATIC pathway - PRostate cancer diAGnosis and MAnagement Triage In Clinical care.

Sharma A. et al, (2026), BJU Int, 137, 849 - 857

DNA-induced conformational changes in SPRTN relieve its auto-inhibitory effect on protease activity.

Song W. et al, (2026), bioRxiv

A preclinical setup for spatially fractionated radiation therapy with electrons.

Taylor ERJF. et al, (2026), Med Phys, 53

Real-time intraoperative depth estimation in transsphenoidal surgery using deep learning: A feasibility study.

Zanier O. et al, (2026), J Clin Neurosci, 147

Population-Based Identification of Clonal Hematopoiesis Using Peripheral Blood Whole-Genome Sequencing in Japan.

Chi S. et al, (2026), Cancer Sci

Structure-guided optimisation of fenofibrate-derived oxidative phosphorylation inhibitors to modify tumour hypoxia.

Holt-Martyn JP. et al, (2026), RSC Med Chem

Integrated epidemiological and molecular data inform the relationship between precancer and cancer states of esophageal adenocarcinoma.

Zamani SA. et al, (2026), Nat Med

Committee on Medical Aspects of Radiation in the Environment (COMARE) Twentieth report Risks of cardiovascular disease from exposure to ionising radiation

de Vocht F. et al, (2026)

DNA methylation signatures of mismatch repair-deficient colorectal cancer

Ward R. et al, (2026)

Generation of biologically responsive colon-like intestinal tissue patches from human induced pluripotent stem cells using a rapid co-differentiation platform.

Dalleywater W. et al, (2026), Stem Cell Res Ther

Hepatobiliary surgical training in a changing educational landscape: An 18-year longitudinal analysis of a high-volume international fellowship programme.

Wettstein D. et al, (2026), Eur J Surg Oncol, 52

Nonsense-mediated mRNA decay inhibition reshapes the cancer immunopeptidome.

Vendramin R. et al, (2026), Immunity

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