ImmuneLENS characterizes systemic immune dysregulation in aging and cancer.
Bentham R. et al, (2025), Nat Genet, 57, 694 - 705
FAT1 alterations contribute to chromosomal instability in cancer cells
Lu W-T. and Kanu N., (2025), NATURE CELL BIOLOGY, 27, 12 - 13
Prospective validation of ORACLE, a clonal expression biomarker associated with survival of patients with lung adenocarcinoma.
Biswas D. et al, (2025), Nat Cancer, 6, 86 - 101
TRACERx analysis identifies a role for FAT1 in regulating chromosomal instability and whole-genome doubling via Hippo signalling.
Lu W-T. et al, (2025), Nat Cell Biol, 27, 154 - 168
Ultrasensitive ctDNA detection for preoperative disease stratification in early-stage lung adenocarcinoma.
Black JRM. et al, (2025), Nat Med, 31, 70 - 76
Replication timing alterations are associated with mutation acquisition during breast and lung cancer evolution
Dietzen M. et al, (2024), Nature Communications, 15
MHC Hammer reveals genetic and non-genetic HLA disruption in cancer evolution.
Puttick C. et al, (2024), Nat Genet, 56, 2121 - 2131
Author Correction: The evolution of lung cancer and impact of subclonal selection in TRACERx.
Frankell AM. et al, (2024), Nature, 631
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling.
Hobor S. et al, (2024), Nat Commun, 15
Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models.
Hynds RE. et al, (2024), Nat Commun, 15
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma.
Pan X. et al, (2024), Nat Cancer, 5, 347 - 363
The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance.
Caswell DR. et al, (2024), Nat Genet, 56, 60 - 73
Antibodies against endogenous retroviruses promote lung cancer immunotherapy.
Ng KW. et al, (2023), Nature, 616, 563 - 573
Body composition and lung cancer-associated cachexia in TRACERx.
Al-Sawaf O. et al, (2023), Nat Med, 29, 846 - 858
Evolutionary characterization of lung adenocarcinoma morphology in TRACERx.
Karasaki T. et al, (2023), Nat Med, 29, 833 - 845
Genomic-transcriptomic evolution in lung cancer and metastasis.
Martínez-Ruiz C. et al, (2023), Nature, 616, 543 - 552
The evolution of lung cancer and impact of subclonal selection in TRACERx.
Frankell AM. et al, (2023), Nature, 616, 525 - 533