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Most trial drugs can cause unwanted reactions known as side effects.  It is of high importance to report any side effect you may experience while on a trial.  Please refer to the patient information sheet (PIS) for specific side effects of the trial drug/s.

We would like you to call us immediately on the number provided on the PIS or call 999 when advised to do so if you experience the following symptoms:

  • Chest pain
  • Difficulty breathing
  • Generally unwell
  • Shivering episodes or flu like symptoms
  • Temperature above 37.5oc or a Temperature below 36oc
  • Being sick (vomiting)
  • Diarrhoea (4 or more times in 24hrs)
  • Swollen or painful legs
  • Sore mouth that makes eating and drinking difficult
  • Bleeding or unusual bruising.

Call us on the EPCU numbers provided within 24hrs if you experience the following symptoms:

  • Itching or painful skin changes/rash.
  • Sore watery eyes
  • Increase pain
  • Constipation
  • Nausea (feeling sick)
  • Diarrhoea 2-4 loose stools/bowel movement in 24hrs
  • Sore mouth, but able to eat and drink.

Please monitor the following symptoms and report if things get worse:

  • Tiredness
  • Skin changes that isn’t itching or painful
  • Mood changes
  • Difficulty coping with the treatment; Loss of appetite.

These are a guide – with clinical trials there is always the possibility of coming across side effects which have not yet been seen, if you feel a change in yourself from normal, please contact us on the phone numbers provided: