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Publications

3-Bromopyruvate-Mediated MCT1-Dependent Metabolic Perturbation Sensitizes Triple Negative Breast Cancer Cells to Ionizing Radiation

VALLIS K. et al, (2021), Cancer and Metabolism

Combining External Beam Radiation and Radionuclide Therapies: Rationale, Radiobiology, Results and Roadblocks.

Abbott EM. et al, (2021), Clin Oncol (R Coll Radiol)

Radioimmunotherapy for Brain Metastases: The Potential for Inflammation as a Target of Choice

Corroyer-Dulmont A. et al, (2021), Frontiers in Oncology, 11

Expanding the chemical functionality of DNA nanomaterials generated by rolling circle amplification.

Baker YR. et al, (2021), Nucleic Acids Res

A phosphate binding pocket is a key determinant of exo- versus endo-nucleolytic activity in the SNM1 nuclease family.

Baddock HT. et al, (2021), Nucleic acids research

A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells.

Dagg RA. et al, (2021), Nat Commun, 12

Irradiation at ultra-high (FLASH) dose rates reduces acute normal tissue toxicity in the mouse gastrointestinal system.

Ruan J-L. et al, (2021), Int J Radiat Oncol Biol Phys

Structural and mechanistic insights into the Artemis endonuclease and strategies for its inhibition.

Yosaatmadja Y. et al, (2021), Nucleic Acids Res

Oligonucleotide-Functionalized Gold Nanoparticles for Synchronous Telomerase Inhibition, Radiosensitization and Delivery of Theranostic Radionuclides

VALLIS K., (2021), Molecular Pharmaceutics

ADGRL4/ELTD1 expression in breast cancer cells induces vascular normalisation and immune suppression.

Sheldon H. et al, (2021), Mol Cancer Res

Deregulation of HLA-I in cancer and its central importance for immunotherapy.

Hazini A. et al, (2021), J Immunother Cancer, 9

Flow Radiocytometry Using Droplet Optofluidics

Ha B. et al, (2021), Biosensors and Bioelectronics, 113565 - 113565

Introduction to the National Cancer Imaging Translational Accelerator (NCITA): a UK-wide infrastructure for multicentre clinical translation of cancer imaging biomarkers.

McAteer MA. et al, (2021), Br J Cancer

The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling.

Moon EJ. et al, (2021), Nat Commun, 12

What aspects of illness influence public preferences for healthcare priority setting? A discrete choice experiment in the UK

MORRELL E. et al, (2021), PharmacoEconomics

Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain.

Brand M. et al, (2021), J Med Chem

Zap-Pano: a Photocaged pro-drug of the KDAC inhibitor panobinostat

Troelsen K. et al, (2021), ChemMedChem

Clinical interpretation of whole-genome and whole-transcriptome sequencing for precision oncology.

Jobanputra V. et al, (2021), Semin Cancer Biol

Combining sonodynamic therapy with chemoradiation for the treatment of pancreatic cancer

Browning R. et al, (2021), Journal of Controlled Release

Nanopore sequencing of single-cell transcriptomes with scCOLOR-seq.

Philpott M. et al, (2021), Nat Biotechnol

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