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Mechanism of Bloom syndrome complex assembly required for double Holliday junction dissolution and genome stability

Journal article

Hodson C. et al, (2022), Proceedings of the National Academy of Sciences, 119, e2109093119 - e2109093119

CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions.

Journal article

Ochi T. et al, (2020), Structure

How Cells Respond to DNA Breaks in Mitosis.

Journal article

Blackford AN. and Stucki M., (2020), Trends Biochem Sci

MDC1 Interacts with TOPBP1 to Maintain Chromosomal Stability during Mitosis.

Journal article

Leimbacher P-A. et al, (2019), Mol Cell, 74, 571 - 583.e8

Structural Insight into BLM Recognition by TopBP1.

Journal article

Sun L. et al, (2017), Structure, 25, 1582 - 1588.e3

PGBD5 promotes site-specific oncogenic mutations in human tumors.

Journal article

Henssen AG. et al, (2017), Nat Genet, 49, 1005 - 1014

ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response.

Journal article

Blackford AN. and Jackson SP., (2017), Mol Cell, 66, 801 - 817

Synthetic lethality between PAXX and XLF in mammalian development.

Journal article

Balmus G. et al, (2016), Genes Dev, 30, 2152 - 2157

Specific Roles of XRCC4 Paralogs PAXX and XLF during V(D)J Recombination.

Journal article

Lescale C. et al, (2016), Cell Rep, 16, 2967 - 2979

TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism.

Journal article

Harley ME. et al, (2016), Nat Genet, 48, 36 - 43

USP4 Auto-Deubiquitylation Promotes Homologous Recombination.

Journal article

Wijnhoven P. et al, (2015), Mol Cell, 60, 362 - 373

BOD1L Is Required to Suppress Deleterious Resection of Stressed Replication Forks.

Journal article

Higgs MR. et al, (2015), Mol Cell, 59, 462 - 477

TopBP1 interacts with BLM to maintain genome stability but is dispensable for preventing BLM degradation.

Journal article

Blackford AN. et al, (2015), Mol Cell, 57, 1133 - 1141

TOPBP1 recruits TOP2A to ultra-fine anaphase bridges to aid in their resolution.

Journal article

Broderick R. et al, (2015), Nat Commun, 6

DNA Ligases


Blackford AN., (2013), Brenner's Encyclopedia of Genetics: Second Edition, 371 - 372

The DNA translocase activity of FANCM protects stalled replication forks.

Journal article

Blackford AN. et al, (2012), Hum Mol Genet, 21, 2005 - 2016

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