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Publications

Single-cell immune multi-omics and repertoire analyses in pancreatic ductal adenocarcinoma reveal differential immunosuppressive mechanisms within different tumour microenvironments

Sivakumar S. et al, (2023)

A role for SETD2 loss in tumorigenesis through DNA methylation dysregulation.

Javaid H. et al, (2023), BMC Cancer, 23

scQCEA: a framework for annotation and quality control report of single-cell RNA-sequencing data.

Nassiri I. et al, (2023), BMC Genomics, 24

Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.

Pairo-Castineira E. et al, (2023), Nature, 619

Characterisation of the genetic determinants of context specific DNA methylation in primary monocytes

Gilchrist JJ. et al, (2023)

GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.

Pairo-Castineira E. et al, (2023), Nature, 617, 764 - 768

Deep sequencing of the T cell Receptor reveals common and reproducible CD8+signatures of response to checkpoint immunotherapy

Watson RA. et al, (2023)

IFNγ signaling in cytotoxic T cells restricts anti-tumor responses by inhibiting the maintenance and diversity of intra-tumoral stem-like T cells.

Mazet JM. et al, (2023), Nat Commun, 14

Germline variants associated with toxicity to immune checkpoint blockade.

Groha S. et al, (2022), Nat Med

IL7 genetic variation and toxicity to immune checkpoint blockade in patients with melanoma.

Taylor CA. et al, (2022), Nat Med

Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19.

Kotanidis CP. et al, (2022), Lancet Digit Health, 4, e705 - e716

Genome-wide association study of leprosy in Malawi and Mali.

Gilchrist JJ. et al, (2022), PLoS Pathog, 18

Natural Killer cells demonstrate distinct eQTL and transcriptome-wide disease associations, highlighting their role in autoimmunity.

Gilchrist JJ. et al, (2022), Nat Commun, 13

Use of cemiplimab for advanced cutaneous squamous cell carcinoma: first real-world data from a UK perspective - a retrospective review

Nestor LA. et al, (2022), BRITISH JOURNAL OF DERMATOLOGY, 187, 107 - 108

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity.

COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium. Electronic address: julian.knight@well.ox.ac.uk None. and COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium None., (2022), Cell, 185, 916 - 938.e58

Phenotyping of cutaneous toxicities in patients with metastatic malignant melanoma treated with immune checkpoint blockade therapy at a UK tertiary care centre.

Ye W. et al, (2022), Clin Exp Dermatol, 47, 448 - 450

ACTR1A has pleiotropic effects on risk of leprosy, inflammatory bowel disease and atopy

Gilchrist JJ. et al, (2022)

A frequent ancestral NFKB1 variant predicts risk of infection or allergy

Chong AY. et al, (2022)

An immunodominant NP105-113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease.

Peng Y. et al, (2022), Nat Immunol, 23, 50 - 61

Deep sequencing of the T-cell receptor reveals common and reproducible CD8 T-cell receptor signatures of response to checkpoint immunotherapy

Watson RA. et al, (2022), ANNALS OF ONCOLOGY, 33, S878 - S879

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