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Publications

Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning.

Sirinukunwattana K. et al, (2021), Gut, 70, 544 - 554

In-depth Clinical and Biological Exploration of DNA Damage Immune Response as a Biomarker for Oxaliplatin Use in Colorectal Cancer.

Malla SB. et al, (2021), Clin Cancer Res, 27, 288 - 300

Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification.

Kleeman SO. et al, (2020), Gut, 69, 1092 - 1103

The interleukin 22 pathway interacts with mutant KRAS to promote poor prognosis in colon cancer.

McCuaig S. et al, (2020), Clin Cancer Res

TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts.

Fielden J. et al, (2020), Nat Commun, 11

Deep learning for prediction of colorectal cancer outcome: a discovery and validation study.

Skrede O-J. et al, (2020), Lancet, 395, 350 - 360

Loss of expression of ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN

Beggs AD. et al, (2019)

Tumour-infiltrating CD8+ lymphocytes and colorectal cancer recurrence by tumour and nodal stage.

Glaire MA. et al, (2019), Br J Cancer, 121, 474 - 482

Targeted next generation sequencing reveals a common genetic pathway for colorectal cancers with chromosomal instability and those with microsatellite and chromosome stability.

Ham-Karim HA. et al, (2019), Pathol Res Pract, 215

Guidelines for using sigQC for systematic evaluation of gene signatures.

Dhawan A. et al, (2019), Nat Protoc, 14, 1377 - 1400

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance.

Li N. et al, (2019), Oncogenesis, 8

PIK3CA (phosphoinositide-3-kinase, catalytic, alpha polypeptide)

Phillips J. and Domingo E., (2019), Atlas of Genetics and Cytogenetics in Oncology and Haematology

POLD1 (DNA polymerase delta 1, catalytic subunit) pages

Domingo E., (2019), Atlas of Genetics and Cytogenetics in Oncology and Haematology

POLE (DNA polymerase epsilon, catalytic subunit)

Domingo E., (2019), Atlas of Genetics and Cytogenetics in Oncology and Haematology

The evolutionary landscape of colorectal tumorigenesis.

Cross W. et al, (2018), Nat Ecol Evol, 2, 1661 - 1672

Mutation burden and other molecular markers of prognosis in colorectal cancer treated with curative intent: results from the QUASAR 2 clinical trial and an Australian community-based series.

Domingo E. et al, (2018), Lancet Gastroenterol Hepatol, 3, 635 - 643

Prognostic markers for colorectal cancer: estimating ploidy and stroma.

Danielsen HE. et al, (2018), Ann Oncol, 29, 616 - 623

Mutation burden and other molecular markers of prognosis in the QUASAR2 clinical trial of colorectal cancer treated with curative intent

Domingo E. et al, (2018), Lancet Gastroenterology and Hepatology, 3

Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution.

Baker A-M. et al, (2017), Nat Commun, 8

Pharmacoproteomic characterisation of human colon and rectal cancer.

Frejno M. et al, (2017), Mol Syst Biol, 13

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