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Publications

Hypoxia-induced SETX links replication stress with the unfolded protein response

Ramachandran S. et al, (2020)

AKT inhibition as a strategy for targeting hypoxic HPV-positive HNSCC.

Göttgens E-L. et al, (2020), Radiother Oncol, 149, 1 - 7

A New Assay to Measure Intestinal Crypt Survival after Irradiation: Challenges and Opportunities.

Muschel RJ. et al, (2020), Cancer Res, 80, 927 - 928

Meeting report of the 16th international congress of radiation research and the 12th international symposium on chromosomal aberrations.

Williams K. et al, (2020), J Radiol Prot, 40, 361 - 365

Corrigendum: Ultra-High Dose Rate (FLASH) Radiotherapy: Silver Bullet or Fool's Gold?

Wilson JD. et al, (2020), Front Oncol, 10

Hypoxia-activated pro-drugs of the KDAC inhibitor vorinostat (SAHA)

Calder EDD. et al, (2020), Tetrahedron

Ultra-high dose rate (FLASH) radiotherapy: Silver bullet or fool’s gold?

Wilson JD. et al, (2019), Frontiers in Oncology

Meeting report on ICRR2019, the 16th International Congress on Radiation Research.

Williams KJ. et al, (2019), Int J Radiat Biol, 1 - 5

Hypoxia-Activated Pro-Drugs of the KDAC Inhibitor Vorinostat (SAHA)

Calder EDD. et al, (2019)

Inhibition of CD4/CDK6 enhances radiosensitivity of HPV negative head and neck squamous cell carcinomas.

Göttgens E-L. et al, (2019), Int J Radiat Oncol Biol Phys

CDK4/CDK6 inhibition radiosensitises HPV-neg HNSCC through inhibition of homologous recombination

Gottgens E. et al, (2019), RADIOTHERAPY AND ONCOLOGY, 133, S129 - S130

Hypoxia-activated small molecule-induced gene expression.

Collins SL. et al, (2018), ACS Chem Biol

Replication Stress Drives Constitutive Activation of the DNA Damage Response and Radioresistance in Glioblastoma Stem-like Cells.

Carruthers RD. et al, (2018), Cancer Res, 78, 5060 - 5071

Hypoxia activated small molecule induced gene expression

Collins S. et al, (2018), ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 256

Hypoxia-activated prodrugs of the KDAC inhibitor panobinostat

Calder E. et al, (2018), ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 256

BET bromodomain ligands: Probing the WPF shelf to improve BRD4 bromodomain affinity and metabolic stability.

Jennings LE. et al, (2018), Bioorg Med Chem, 26, 2937 - 2957

Challenges to DNA replication in hypoxic conditions.

Ng N. et al, (2018), FEBS J, 285, 1563 - 1571

WSB-1 regulates the metastatic potential of hormone receptor negative breast cancer.

Poujade F-A. et al, (2018), Br J Cancer, 118, 1229 - 1237

DNA replication stress due to long gene expression causes radioresistance in GBM stem cells

Carruthers R. et al, (2018), RADIOTHERAPY AND ONCOLOGY, 127, S193 - S193

HPV, hypoxia and radiation response in head and neck cancer.

Göttgens E-L. et al, (2018), Br J Radiol

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