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Publications

Selective modulation by PARP-1 of HIF-1α-recruitment to chromatin during hypoxia is required for tumor adaptation to hypoxic conditions.

Martí JM. et al, (2021), Redox Biol, 41

Hypoxia inducible factors regulate hepatitis B virus replication by activating the basal core promoter

Wing PAC. et al, (2021), Journal of Hepatology

Cyclic Hypoxia: An Update on Its Characteristics, Methods to Measure It and Biological Implications in Cancer.

Bader SB. et al, (2020), Cancers (Basel), 13

Pharmacological Inhibition of ATR Can Block Autophagy through an ATR-Independent Mechanism.

Bowler E. et al, (2020), iScience, 23

Anticancer Imidazoacridinone C-1311 is Effective in Androgen-Dependent and Androgen-Independent Prostate Cancer Cells.

Niemira M. et al, (2020), Biomedicines, 8

AKT inhibition as a strategy for targeting hypoxic HPV-positive HNSCC.

Göttgens E-L. et al, (2020), Radiother Oncol, 149, 1 - 7

Hypoxia-induced SETX links replication stress with the unfolded protein response

Ramachandran S. et al, (2020)

Hypoxia-activated pro-drugs of the KDAC inhibitor vorinostat (SAHA)

Calder EDD. et al, (2020), Tetrahedron, 76

A New Assay to Measure Intestinal Crypt Survival after Irradiation: Challenges and Opportunities.

Muschel RJ. et al, (2020), Cancer Res, 80, 927 - 928

Meeting report of the 16th international congress of radiation research and the 12th international symposium on chromosomal aberrations.

Williams K. et al, (2020), J Radiol Prot, 40, 361 - 365

Meeting report on ICRR2019, the 16th International Congress on Radiation Research.

Williams KJ. et al, (2020), Int J Radiat Biol, 96, 167 - 171

Corrigendum: Ultra-High Dose Rate (FLASH) Radiotherapy: Silver Bullet or Fool's Gold?

Wilson JD. et al, (2020), Front Oncol, 10

Targeting tumor hypoxia

Skwarski M. et al, (2020), Cancer Drug Discovery and Development, 265 - 299

Inhibition of CDK4/CDK6 Enhances Radiosensitivity of HPV Negative Head and Neck Squamous Cell Carcinomas.

Göttgens E-L. et al, (2019), Int J Radiat Oncol Biol Phys, 105, 548 - 558

Hypoxia-Activated Pro-Drugs of the KDAC Inhibitor Vorinostat (SAHA)

Calder EDD. et al, (2019)

CDK4/CDK6 inhibition radiosensitises HPV-neg HNSCC through inhibition of homologous recombination

Gottgens E. et al, (2019), RADIOTHERAPY AND ONCOLOGY, 133, S129 - S130

HPV, hypoxia and radiation response in head and neck cancer.

Göttgens E-L. et al, (2019), Br J Radiol, 92

Ultra-High Dose Rate (FLASH) Radiotherapy: Silver Bullet or Fool's Gold?

Wilson JD. et al, (2019), Front Oncol, 9

Hypoxia-Activated, Small-Molecule-Induced Gene Expression.

Collins SL. et al, (2018), ACS Chem Biol, 13, 3354 - 3360

Replication Stress Drives Constitutive Activation of the DNA Damage Response and Radioresistance in Glioblastoma Stem-like Cells.

Carruthers RD. et al, (2018), Cancer Res, 78, 5060 - 5071

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