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Publications

ZBTB2 links p53 deficiency to HIF-1-mediated hypoxia signaling to promote cancer aggressiveness.

Koyasu S. et al, (2022), EMBO reports

How the histological structure of some lung cancers shaped almost 70 years of radiobiology

Worth K. et al, (2022), British Journal of Cancer

Identification of Histone Peptide Binding Specificity and Small-Molecule Ligands for the TRIM33α and TRIM33β Bromodomains

Sekirnik AR. et al, (2022), ACS Chemical Biology

A fluorescent probe strategy for the detection and discrimination of hydrogen peroxide and peroxynitrite in cells.

Bolland HR. et al, (2022), Chem Commun (Camb)

DNA-structured mathematical model of cell-cycle progression in cyclic hypoxia.

Celora GL. et al, (2022), J Theor Biol

Elucidating the role of transiently hypoxic tumour cells on radiation resistance

HIGGINS G. and HAMMOND E., (2022), British Journal of Cancer

SPINK1 as a plasma marker for tumor hypoxia and a therapeutic target for radiosensitization

Suwa T. et al, (2021), JCI Insight, 6

A DNA-structured mathematical model of cell-cycle progression in cyclic hypoxia

Celora GL. et al, (2021)

Replication catastrophe induced by cyclic hypoxia leads to increased APOBEC3B activity.

Bader SB. et al, (2021), Nucleic Acids Res, 49, 7492 - 7506

Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain.

Brand M. et al, (2021), J Med Chem

Zap-Pano: a Photocaged pro-drug of the KDAC inhibitor panobinostat

Troelsen K. et al, (2021), ChemMedChem

Links between the unfolded protein response and the DNA damage response in hypoxia: a systematic review.

Bolland H. et al, (2021), Biochem Soc Trans, 49, 1251 - 1263

Hypoxia-induced SETX links replication stress with the unfolded protein response.

Ramachandran S. et al, (2021), Nat Commun, 12

Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor.

Skwarska A. et al, (2021), Cell Chem Biol

Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor

Skwarska A. et al, (2021)

Selective modulation by PARP-1 of HIF-1α-recruitment to chromatin during hypoxia is required for tumor adaptation to hypoxic conditions.

Martí JM. et al, (2021), Redox Biol, 41

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.

Klionsky DJ. et al, (2021), Autophagy, 17, 1 - 382

Hypoxia inducible factors regulate hepatitis B virus replication by activating the basal core promoter

Wing PAC. et al, (2021), Journal of Hepatology

Cyclic Hypoxia: An Update on Its Characteristics, Methods to Measure It and Biological Implications in Cancer.

Bader SB. et al, (2020), Cancers (Basel), 13

Pharmacological Inhibition of ATR Can Block Autophagy through an ATR-Independent Mechanism.

Bowler E. et al, (2020), iScience, 23

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