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Publications

Antibody-based Imaging of Bioreductive Prodrug Release in Hypoxia

Tosun C. et al, (2023), JACS Au

Hypoxia-induced transcriptional stress is mediated by ROS-induced R-loops

MA T. et al, (2023), Nucleic Acids Research

Corrigendum to "A DNA-structured mathematical model of cell-cycle progression in cyclic hypoxia" [J. Theor. Biol. 545 (2022) 111104].

Celora GL. et al, (2023), J Theor Biol, 571

Hypoxia-mediated regulation of DDX5 through decreased chromatin accessibility and post-translational targeting restricts R-loop accumulation.

Leszczynska KB. et al, (2023), Mol Oncol, 17, 1173 - 1191

Oxali(IV)Fluors: Fluorescence Responsive Oxaliplatin(IV) Complexes Identify a Hypoxia-Dependent Reduction in Cancer Cells.

Boulet MHC. et al, (2023), J Am Chem Soc, 145, 12998 - 13002

How the histological structure of some lung cancers shaped almost 70 years of radiobiology.

Worth KR. et al, (2023), Br J Cancer, 128, 407 - 412

Two Color Imaging of Different Hypoxia Levels in Cancer Cells.

Wallabregue ALD. et al, (2023), J Am Chem Soc, 145, 2572 - 2583

ZBTB2 links p53 deficiency to HIF-1-mediated hypoxia signaling to promote cancer aggressiveness.

Koyasu S. et al, (2023), EMBO Rep, 24

Identification of Histone Peptide Binding Specificity and Small-Molecule Ligands for the TRIM33α and TRIM33β Bromodomains.

Sekirnik AR. et al, (2022), ACS Chem Biol, 17, 2753 - 2768

Small-molecule Polθ inhibitors provide safe and effective tumor radiosensitization in preclinical models

Rodriguez-Berriguete G. et al, (2022)

A fluorescent probe strategy for the detection and discrimination of hydrogen peroxide and peroxynitrite in cells.

Bolland HR. et al, (2022), Chem Commun (Camb), 58, 10699 - 10702

A DNA-structured mathematical model of cell-cycle progression in cyclic hypoxia.

Celora GL. et al, (2022), J Theor Biol, 545

Elucidating the role of transiently hypoxic tumour cells on radiation resistance.

Higgins GS. and Hammond EM., (2022), Br J Cancer, 126, 971 - 972

A DNA-structured mathematical model of cell-cycle progression in cyclic hypoxia

Celora GL. et al, (2022), Journal of Theoretical Biology

Zap-Pano: a Photocaged Prodrug of the KDAC Inhibitor Panobinostat.

Troelsen KS. et al, (2021), ChemMedChem, 16, 3691 - 3700

SPINK1 as a plasma marker for tumor hypoxia and a therapeutic target for radiosensitization.

Suwa T. et al, (2021), JCI Insight, 6

Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor.

Skwarska A. et al, (2021), Cell Chem Biol, 28, 1258 - 1270.e13

Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain.

Brand M. et al, (2021), J Med Chem, 64, 10102 - 10123

Replication catastrophe induced by cyclic hypoxia leads to increased APOBEC3B activity.

Bader SB. et al, (2021), Nucleic Acids Res, 49, 7492 - 7506

Hypoxia inducible factors regulate hepatitis B virus replication by activating the basal core promoter.

Wing PAC. et al, (2021), J Hepatol, 75, 64 - 73

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