JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors.
Journal article
Pennel KAF. et al, (2024), J Exp Clin Cancer Res, 43
Intra-prostatic tumour evolution, steps in metastatic spread and histogenomic associations revealed by integration of multi-region whole-genome sequencing with histopathological features.
Journal article
Rao S. et al, (2024), Genome Med, 16
Leveraging GWAS: Path to Prevention? - Letter.
Journal article
Peters U. and Tomlinson I., (2024), Cancer Prev Res (Phila), 17
Multiplex analysis of intratumoural immune infiltrate and prognosis in patients with stage II-III colorectal cancer from the SCOT and QUASAR 2 trials: a retrospective analysis.
Journal article
Frei AL. et al, (2024), Lancet Oncol, 25, 198 - 211
Utilizing Human Genetics to Develop Chemoprevention for Cancer-Too Good an Opportunity to be Missed.
Journal article
Peters U. and Tomlinson I., (2024), Cancer Prev Res (Phila), 17, 7 - 12
Adult stem cell activity in naked mole rats for long-term tissue maintenance
Journal article
IRSHAD S., (2023), Nature Communications
Adult stem cell activity in naked mole rats for long-term tissue maintenance.
Journal article
Montazid S. et al, (2023), Nat Commun, 14
A rapid method for generating transplantable and biologically responsive colonic tissue from human induced pluripotent stem cells
Preprint
Dalleywater W. et al, (2023)
Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations.
Journal article
Thomas M. et al, (2023), Nat Commun, 14
Accounting for intensity variation in image analysis of large-scale multiplexed clinical trial datasets.
Journal article
Frei AL. et al, (2023), J Pathol Clin Res
Transformer-based biomarker prediction from colorectal cancer histology: A large-scale multicentric study.
Journal article
Wagner SJ. et al, (2023), Cancer Cell
Functional analysis reveals driver cooperativity and novel mechanisms in endometrial carcinogenesis.
Journal article
Brown M. et al, (2023), EMBO Mol Med
Genomic Evolution and Transcriptional Changes in the Evolution of Prostate Cancer into Neuroendocrine and Ductal Carcinoma Types.
Journal article
Rao SR. et al, (2023), Int J Mol Sci, 24
Author Correction: Germline de novo mutations in families with Mendelian cancer syndromes caused by defects in DNA repair.
Journal article
Sherwood K. et al, (2023), Nat Commun, 14
Spectrum and Frequency of Germline FANCM Protein-Truncating Variants in 44,803 European Female Breast Cancer Cases.
Journal article
Figlioli G. et al, (2023), Cancers (Basel), 15
Germline de novo mutations in families with Mendelian cancer syndromes caused by defects in DNA repair.
Journal article
Sherwood K. et al, (2023), Nat Commun, 14
Genome-wide analyses characterize shared heritability among cancers and identify novel cancer susceptibility regions.
Journal article
Lindström S. et al, (2023), J Natl Cancer Inst, 115, 712 - 732
Multi-trait genome-wide association study identifies a novel endometrial cancer risk locus that associates with testosterone levels
Journal article
Wang X. et al, (2023), iScience, 26
FANCM missense variants and breast cancer risk: a case-control association study of 75,156 European women.
Journal article
Figlioli G. et al, (2023), Eur J Hum Genet, 31, 578 - 587
Exploring the complex relationship between gut microbiota and risk of colorectal neoplasia using bidirectional Mendelian Randomization analysis.
Journal article
Li W. et al, (2023), Cancer Epidemiol Biomarkers Prev