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The antitumorigenic roles of BRCA1-BARD1 in DNA repair and replication.

Journal article

Tarsounas M. and Sung P., (2020), Nat Rev Mol Cell Biol

BRCA2 abrogation triggers innate immune responses potentiated by treatment with PARP inhibitors.

Journal article

Reisländer T. et al, (2019), Nature communications, 10

Chlorambucil targets BRCA1/2-deficient tumours and counteracts PARP inhibitor resistance.

Journal article

Tacconi EM. et al, (2019), EMBO Mol Med, 11

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality.

Journal article

Gogola E. et al, (2019), Cancer Cell, 35, 950 - 952

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality.

Journal article

Gogola E. et al, (2018), Cancer Cell, 33, 1078 - 1093.e12

Tc-99m-duramycin imaging reveals variable tissue toxicity of cancer drugs

Conference paper

Sneddon D. et al, (2018), JOURNAL OF NUCLEAR MEDICINE, 59

BRCA1 and BRCA2 tumor suppressors protect against endogenous acetaldehyde toxicity.

Journal article

Tacconi EM. et al, (2017), EMBO Mol Med, 9, 1398 - 1414

FANCD2 limits replication stress and genome instability in cells lacking BRCA2.

Journal article

Michl J. et al, (2016), Nat Struct Mol Biol, 23, 755 - 757

Interplay between Fanconi anemia and homologous recombination pathways in genome integrity.

Journal article

Michl J. et al, (2016), EMBO J, 35, 909 - 923

Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds.

Journal article

Zimmer J. et al, (2016), Mol Cell, 61, 449 - 460

How homologous recombination maintains telomere integrity

Journal article

Tacconi EMC. and Tarsounas M., (2015), Chromosoma, 124, 119 - 130

How homologous recombination maintains telomere integrity.

Journal article

Tacconi EMC. and Tarsounas M., (2015), Chromosoma, 124, 119 - 130

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