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The HDAC inhibitor zabadinostat is a systemic regulator of adaptive immunity.

Journal article

Liu G. et al, (2023), Commun Biol, 6

Immune modulation underpins the anti-cancer activity of HDAC inhibitors.

Journal article

Blaszczak W. et al, (2021), Mol Oncol

PRMT5 promotes cancer cell migration and invasion through the E2F pathway.

Journal article

Barczak W. et al, (2020), Cell Death Dis, 11

Tudor-domain protein PHF20L1 reads lysine methylated retinoblastoma tumour suppressor protein.

Journal article

Carr SM. et al, (2017), Cell Death Differ, 24, 2139 - 2149

Transfection

Chapter

Sheikh S. et al, (2017), Basic Science Methods for Clinical Researchers, 191 - 209

CBP/p300 Bromodomains Regulate Amyloid-like Protein Aggregation upon Aberrant Lysine Acetylation.

Journal article

Olzscha H. et al, (2017), Cell Chem Biol, 24, 9 - 23

Bromodomains control amyloid-like aggregation of aberrantly acetylated proteins.

Conference paper

Olzscha H. et al, (2017), MOLECULAR BIOLOGY OF THE CELL, 28

Linking H1 with chromatin and growth control.

Journal article

Munro S. and La Thangue NB., (2017), Mol Cell Oncol, 4

TLR Adaptor Protein MYD88 Mediates Sensitivity to HDAC Inhibitors via a Cytokine-Dependent Mechanism.

Journal article

New M. et al, (2016), Cancer Res, 76, 6975 - 6987

Regulation of actin nucleation and autophagosome formation.

Journal article

Coutts AS. and La Thangue NB., (2016), Cell Mol Life Sci, 73, 3249 - 3263

Structural analysis of human KDM5B guides histone demethylase inhibitor development.

Journal article

Johansson C. et al, (2016), Nat Chem Biol, 12, 539 - 545

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