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Repeat expansions confer WRN dependence in microsatellite-unstable cancers.

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van Wietmarschen N. et al, (2020), Nature, 586, 292 - 298

The SNM1A DNA repair nuclease.

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Baddock HT. et al, (2020), DNA Repair (Amst), 95

Genetic and functional insights into CDA-I prevalence and pathogenesis.

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Olijnik A-A. et al, (2020), J Med Genet

XPF-ERCC1: Linchpin of DNA crosslink repair

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MCHUGH P., (2020), PLoS Genetics

The analysis of DNA interstrand crosslinks and their repair by the modified Comet assay


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A hydroxamic-acid-containing nucleoside inhibits DNA repair nuclease SNM1A.

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Doherty W. et al, (2019), Org Biomol Chem

Microhomologies are prevalent at Cas9-induced larger deletions

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Owens DDG. et al, (2019), Nucleic Acids Research

Antiviral activity of bone morphogenetic proteins and activins.

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Eddowes LA. et al, (2019), Nat Microbiol, 4, 339 - 351

Squaramide-Based 5’-Phosphate Replacements Bind to the DNA Repair Exonuclease SNM1A

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Replication Fork Reversal during DNA Interstrand Crosslink Repair Requires CMG Unloading.

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Amunugama R. et al, (2018), Cell Rep, 23, 3419 - 3428

In Silico Fragment-Based Design Identifies Subfamily B1 Metallo-β-lactamase Inhibitors.

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Cain R. et al, (2018), J Med Chem, 61, 1255 - 1260

RPA activates the XPF-ERCC1 endonuclease to initiate processing of DNA interstrand crosslinks.

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RPA activates XPF-ERCC1 to initiate the processing of DNA

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Mchugh P. et al, (2017), The EMBO Journal

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