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Publications

The Challenge of Combining Chemo- and Radiotherapy with Checkpoint Kinase Inhibitors.

van Bijsterveldt L. et al, (2020), Clin Cancer Res

An essential role for dNTP homeostasis following CDK-induced replication stress.

Pai C-C. et al, (2019), J Cell Sci

Nucleoporin 54 contributes to homologous recombination repair and post-replicative DNA integrity.

Rodriguez-Berriguete G. et al, (2018), Nucleic Acids Res, 46, 7731 - 7746

Analysis of DNA Metabolism in Fission Yeast.

Antequera F. and Humphrey TC., (2018), Cold Spring Harb Protoc, 2018

DNA Double-Strand Break Repair Assay.

Pai C-C. et al, (2018), Cold Spring Harb Protoc, 2018

Using Pulsed-Field Gel Electrophoresis to Analyze Schizosaccharomyces pombe Chromosomes and Chromosomal Elements.

Pai C-C. et al, (2018), Cold Spring Harb Protoc, 2018

Targeting histone H3K36me3-deficient cancers

Humphrey T., (2018), ANNALS OF ONCOLOGY, 29

Set2 Methyltransferase Facilitates DNA Replication and Promotes Genotoxic Stress Responses through MBF-Dependent Transcription.

Pai C-C. et al, (2017), Cell Rep, 20, 2693 - 2705

MRG15-mediated tethering of PALB2 to unperturbed chromatin protects active genes from genotoxic stress.

Bleuyard J-Y. et al, (2017), Proc Natl Acad Sci U S A, 114, 7671 - 7676

Homologous Recombination and Nonhomologous End-Joining Repair in Yeast

Jones RE. and Humphrey TC., (2016), Genome Stability: From Virus to Human Application, 117 - 135

Variation, Modification, and Reorganization of Broken Chromatin

Humphrey TC. et al, (2016), Chromatin Signaling and Diseases, 197 - 216

A role for human homologous recombination factors in suppressing microhomology-mediated end joining.

Ahrabi S. et al, (2016), Nucleic Acids Res, 44, 5743 - 5757

The spliceosome-associated protein Nrl1 suppresses homologous recombination-dependent R-loop formation in fission yeast.

Aronica L. et al, (2016), Nucleic Acids Res, 44, 1703 - 1717

WEE1 inhibition selectively kills histone H3K36me3-deficient cancers by dNTP starvation

Pfister SX. et al, (2016), CANCER RESEARCH, 76

Use of the HPRT gene to study nuclease-induced DNA double-strand break repair.

Gravells P. et al, (2015), Hum Mol Genet, 24, 7097 - 7110

Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation.

Pfister SX. et al, (2015), Cancer Cell, 28, 557 - 568

Nrl1 is a new spliceosomal factor involved in maintenance of genome stability of S. pombe

Aronica L. et al, (2015), YEAST, 32, S135 - S135

Identifying new targets for cancer drug 5'-fluorouracil.

Humphrey TC., (2015), Cell Cycle, 14

A novel synthetic lethal interaction between the histone mark H3K36me3 and checkpoint kinases

Pfister SX. et al, (2014), EUROPEAN JOURNAL OF CANCER, 50, 71 - 71

SET-ting the stage for DNA repair.

Jha DK. et al, (2014), Nat Struct Mol Biol, 21, 655 - 657

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