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MRI is the method-of-choice  for non-invasive assessment of soft tissue pathology and function.

We are equipped with 3 high-field MRI systems suitable for small animal imaging:

  • 4.7  Tesla with 150 mm imaging volume (Bruker Avance III)
  • 7.0 Tesla with 80 mm imaging volume (Varian VNMRS)
  • 9.4 Tesla with 60 mm imaging volume (Varian VNMRS)

 We have a locally-developed suite of animal handling apparatus, including physiological maintenance and gating controls that are compatible across all MRI scanners, as well as the SPECT(PET)-CT and SARRP systems.

In addition to the conventional scan modes, several locally-developed  high- resolution scans are available including cardio-respiratory gated T1/T2 weighted scans and respiratory gated, constant TR, 2D multi slice  scans.

 Applications enabled by these scans include whole-body DCE-MRI,  MR image-guided radiotherapy of abdominal tumours and high resolution detection of lung tumours.

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Whole body DCE

DCE_movie

 

Xenograft tumour DCE

Image in collaboration with Ruth Muschel group

MRI_Lungs

 

Lung tumour imaging

Image in collaboration with Anderson Ryan group