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Grigory Dianov

Emeritus Professor

Research Summary

My interests over the years have focussed on the proteins and mechanisms involved in the coordination and regulation of Base Excision Repair.

Biography

Professor Grigory Dianov was the Head of Biochemistry at the CRUK/MRC Oxford Institute for Radiation Oncology within the Department of Oncology until May 2018.

He obtained his Doctor of Biological Sciences degree from the Institute of Cytology and Genetics, Siberian Department of the Russian Academy of Sciences at the age of 36 to become the youngest Doctor of Biological Sciences in the country.  The same year Grigory was awarded Lenin’s Komsomol Prize, the highest Russian award for young scientists.  He continued to work at the Institute of Cytology and Genetics as a Professor and Head of the Laboratory of Molecular Mechanisms of Mutagenesis until 1990.  Dr Dianov moved to England and from 1990 - 1993 worked as a Senior Fellow at the Imperial Cancer Research Fund (London) with Dr. Tomas Lindahl (2015 Nobel Prize in Chemistry for DNA Repair mechanisms), where he worked on the basic mechanisms of DNA repair and genome stability.  One of Grigory’s papers published jointly with Dr. Lindahl was cited in the Nobel Prize Committee’s justification for the Nobel Prize.  In 1993 Grigory moved to the United States where he continue his work on DNA repair as a visiting Professor at the Southwestern Medical Center, Dallas with Dr. Errol Friedberg, a legendary figure in DNA repair field and later as a Senior Fellow with Dr. Vilhelm Bohr (National Institute on Ageing, NIH, Baltimore) where he investigated the role of DNA repair in ageing.  In 2000, Dr Dianov moved back to England to become Head of the Biochemistry Group at the Medical Research Council and in 2007 he became Head of Biochemistry at the University of Oxford. 

Grigory is a member of Editorial Board of several international journals and a frequent reviewer for the Grants Council of the Russian Federation Government,  Member of Reviewers Board for the European Research Council, the French National Research Agency, Grant reviewer for Medical Research Council, Cancer Research UK and many international journals.