Katherine Vallis

(2019), 28rd International Symposium on Cerebral Blood Flow, Metabolism and Function and the 13th International Conference on Quantification of Brain Function (BRAIN and BRAIN PET 2017)

Ultrasound-mediated cavitation enhances the delivery of an EGFR-targeting liposomal formulation designed for chemo-radionuclide therapy.

Thomas E. et al, (2019), Theranostics, 9, 5595 - 5609

Impact of inter-cycle changes in dose heterogeneity, biokinetics and tumour volume on dose-based personalisation of administered activity for 177Lu-based treatment

Malcolm J. et al, (2019), JOURNAL OF NUCLEAR MEDICINE, 60

Photon vs proton therapy for reduction of cardiac toxicities in locally advanced lung cancer

Teoh S. et al, (2019), RADIOTHERAPY AND ONCOLOGY, 133, S1051 - S1051

Imaging DNA Damage in vivo following [177Lu] Lu-DOTATATE therapy in a model of pancreatic neuroendocrine cancer

O'Neill E. et al, (2019), EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 46, S196 - S196

Combining ruthenium metallo-intercalators and targeted radionuclide therapy for EGFR-overexpressing oesophageal cancer

Gill MR. et al, (2019), CANCER RESEARCH, 79

Ultrasound-Induced Mircobubble Cavitation For Optimisation Of Tumour Uptake Of Liposome-Based Chemo-Radionuclide Therapy

Vallis KA. et al, (2019), EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 46, S107 - S108

Towards intracellular targeting: Cytosolic delivery using TAT-trimers

Tietz O. et al, (2019), CANCER RESEARCH, 79

Robustness assessment using probabilistic scenarios of intensity modulated proton therapy and volumetric arc therapy in non-small-cell lung cancer: an in-silico radiotherapy planning study

(2018), Spring Meeting for Clinician Scientists in Training 2017

Safety and tumour hypoxia modifying effect of buparlisib with radiotherapy in NSCLC: a phase I dose escalation study

McGowan DR. et al, (2018)

Towards Individualizing Patient Selection in Proton Therapy for Lung Cancer Using the Model-Based Approach

Teoh S. et al, (2018), JOURNAL OF THORACIC ONCOLOGY, 13, S1027 - S1027

Indium-111 afterloading of preformed EGF containing liposomes for molecularly targeted radionuclide delivery via ultrasound induced cavitation

Owen JW. et al, (2018), EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 45, S687 - S687

Targeted alpha therapy with 212Pb or 225Ac: Change in RBE from daughter migration.

Ackerman NL. et al, (2018), Phys Med, 51, 91 - 98

Targeting Micrometastases: The Effect of Heterogeneous Radionuclide Distribution on Tumor Control Probability.

Falzone N. et al, (2018), J Nucl Med, 60, 250 - 258

111In-labelled polymeric nanoparticles incorporating a ruthenium-based radiosensitizer for EGFR-targeted combination therapy in oesophageal cancer cells.

Gill MR. et al, (2018), Nanoscale, 10, 10596 - 10608

MONTE CARLO EVALUATION OF RADIONUCLIDES FOR EARLY BRAIN METASTASES TARGETING

Falzone N. et al, (2018), INTERNAL MEDICINE JOURNAL, 48, 9 - 10

Probabilistic scenarios for assessing setup uncertainty in VMAT and IMPT plans for lung cancer

Teoh S. et al, (2018), RADIOTHERAPY AND ONCOLOGY, 127, S1130 - S1131

MONTE CARLO EVALUATION OF RADIONUCLIDES FOR EARLY BRAIN METASTASES TARGETING

Falzone N. et al, (2018), INTERNAL MEDICINE JOURNAL, 48, 9 - 10

ee-in-one-bullet for oesophageal cancer: replication fork collapse, spindle attachment failure and enhanced radiosensitivity generated by a ruthenium(ii) metallo-intercalator.

Gill MR. et al, (2018), Chem Sci, 9, 841 - 849

Subcellular Targeting of Theranostic Radionuclides.

Bavelaar BM. et al, (2018), Front Pharmacol, 9

Dosimetric evaluation of radionuclides for VCAM-1-targeted radionuclide therapy of early brain metastases.

Falzone N. et al, (2018), Theranostics, 8, 292 - 303

Investigating the Radiosensitization Effects of Gold Nanoparticles in Combination with Megavoltage Radiation on U87 Glioblastoma Cells

Kazmi F. et al, (2018), INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 102, E184 - E184

Monitoring response to anti-angiogenic mTOR inhibitor therapy in vivo using 111In-bevacizumab.

Patel N. et al, (2017), EJNMMI Res, 7

Dosimetric Analysis of Individual Liver Metastases from Colorectal Cancer Following 90 y Microsphere Selective Internal Radiation Therapy

Abbott EM. et al, (2017), INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 99, E132 - E132

Improved outcome of 131I-mIBG treatment through combination with external beam radiotherapy in the SK-N-SH mouse model of neuroblastoma.

Corroyer-Dulmont A. et al, (2017), Radiother Oncol, 124, 488 - 495

Electrically tunable fluidic lens imaging system for laparoscopic fluorescence-guided surgery.

Volpi D. et al, (2017), Biomed Opt Express, 8, 3232 - 3247

Targeted radionuclide therapy in combined-modality regimens.

Gill MR. et al, (2017), Lancet Oncol, 18, e414 - e423

bsorbed dose evaluation of Auger electron-emitting radionuclides: impact of input decay spectra on dose point kernels and S-values.

Falzone N. et al, (2017), Phys Med Biol, 62, 2239 - 2253

Targeting telomerase with radiolabeled inhibitors.

Waghorn PA. et al, (2017), Eur J Med Chem, 125, 117 - 129

n efficient and robust MRI-guided radiotherapy planning approach for targeting abdominal organs and tumours in the mouse.

Kersemans V. et al, (2017), PLoS One, 12

ccumulation of 111In-Labelled EGF-Au-PEG Nanoparticles in EGFR-Positive Tumours is Enhanced by Coadministration of Targeting Ligand.

Song L. et al, (2017), Nanotheranostics, 1, 232 - 243

MRI-guided radiotherapy of the SK-N-SH neuroblastoma xenograft model using a small animal radiation research platform.

Corroyer-Dulmont A. et al, (2017), Br J Radiol, 90

Radiotherapeutic Nanoparticles Containing a Ruthenium-Based Radiosensitizer for EGFR-Positive Oesophageal Cancer

Gill MR. et al, (2017), EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 44, S771 - S771

Corrigendum: A ruthenium polypyridyl intercalator stalls DNA replication forks, radiosensitizes human cancer cells and is enhanced by Chk1 inhibition.

Gill MR. et al, (2016), Sci Rep, 6

EGF-coated gold nanoparticles provide an efficient nano-scale delivery system for the molecular radiotherapy of EGFR-positive cancer.

Song L. et al, (2016), Int J Radiat Biol, 92, 716 - 723

EGF-coated gold nanoparticles provide an efficient nano-scale delivery system for the molecular radiotherapy of EGFR-positive cancer.

Song L. et al, (2016), Int J Radiat Biol, 92, 716 - 723

Synthesis and evaluation of an 18 F-labeled derivative of F3 for targeting surface-expressed nucleolin in cancer and tumor endothelial cells.

Lam PYH. et al, (2016), J Labelled Comp Radiopharm, 59, 492 - 499

enium polypyridyl intercalator stalls DNA replication forks, radiosensitizes human cancer cells and is enhanced by Chk1 inhibition.

Gill MR. et al, (2016), Sci Rep, 6

Development of Radiolabelled Drug Carrier Systems for Molecularly Targeted Radiotherapy

Vallis KA. et al, (2016), Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016;76(14 Suppl):Abstract nr 2161.

MR-based IGRT platform using the KPC transgenic mouse model of pancreatic cancer

Thompson J. et al, (2016), Radiotherapy and Oncology, 119, S250 - S250

SPECT imaging and biodistribution studies of 111In-EGF-Au-PEG nanoparticles in vivo

Vallis KA., (2016)

Development of radiolabelled engineered Bacillus anthracis toxin for MMP imaging

Xavier MA. et al, (2016), 57, 1146 - 1146

Single cell S-value calculations of a stochastic cascade model for Auger-electron emitting radionuclides

Vallis KA. and Falzone N., (2016), J Nucl Med

γH2AX expression in cytological specimens as a biomarker of response to radiotherapy in solid malignancies.

Shah K. et al, (2016), Diagn Cytopathol, 44, 141 - 146

DNA double-strand break repair: a theoretical framework and its application.

Murray PJ. et al, (2016), J R Soc Interface, 13

Realistic single-cell geometry model: Cellular S-value calculations with Geant4, Geant4-DNA and PENELOPE

Falzone N. et al, (2016), EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 43, S401 - S401

Monte Carlo calculated single-cell S-values using a stochastic atomic relaxation model for accurate nuclear data of Auger electron-emitting radionuclides

Falzone N. et al, (2016), EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 43, S228 - S228

I131-MIBG treatment revisited: How important is scheduling when combined with external beam irradiation?

Corroyer-Dulmont A. et al, (2016), JOURNAL OF NUCLEAR MEDICINE, 57

dit of palliative whole brain radiotherapy (WBRT) in patients with non-small cell lung cancer (NSCLC) treated at the Oxford Cancer Centre over 21/2 years

Shakir R. et al, (2016), LUNG CANCER, 91, S52 - S53

Monte Carlo Evaluation of Auger Electron-Emitting Theranostic Radionuclides.

Falzone N. et al, (2015), J Nucl Med, 56, 1441 - 1446

Spatial distribution of Auger electrons emitted from internalised radionuclides in cancer cells: the photoresist autoradiography (PAR) method.

Royle G. et al, (2015), Radiat Prot Dosimetry, 166, 228 - 232

XRCC1 Polymorphism Associated With Late Toxicity After Radiation Therapy in Breast Cancer Patients.

Seibold P. et al, (2015), Int J Radiat Oncol Biol Phys, 92, 1084 - 1092

XRCC1 Polymorphism Associated with Late Toxicity after Radiation Therapy in Breast Cancer Patients

Seibold P. et al, (2015), International Journal of Radiation Oncology Biology Physics, 92, 1084 - 1092

Regional Nodal Irradiation in Early-Stage Breast Cancer.

Whelan TJ. et al, (2015), N Engl J Med, 373, 307 - 316

SU-F-BRD-04: Robustness Analysis of Proton Breast Treatments Using An Alpha-Stable Distribution Parameterization.

Van den Heuvel F. et al, (2015), Med Phys, 42

Breast-conserving surgery with or without irradiation in women aged 65 years or older with early breast cancer (PRIME II): a randomised controlled trial.

Kunkler IH. et al, (2015), Lancet Oncol, 16, 266 - 273

PET and SPECT Imaging for the Acceleration of Anti-Cancer Drug Development.

Hillyar CRT. et al, (2015), Curr Drug Targets, 16, 582 - 591

Relationship between Caffeine and Levels of DNA Repair and Oxidative Stress in Women with and without a BRCA1 Mutation.

Nikitina D. et al, (2015), J Nutrigenet Nutrigenomics, 8, 174 - 184

Monte Carlo evaluation of Auger-electron emitting radionuclides in 3-D cellular models

Falzone N. et al, (2015), EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 42, S116 - S116

Robustness Analysis of Proton Breast Treatments Using An Alpha-Stable Distribution Parameterization

Van den Heuvel F. et al, (2015), MEDICAL PHYSICS, 42, 3526 - 3526

Stereotactic ablative radiotherapy (SABR) for early stage, medically inoperable non-small cell lung cancer (NSCLC): initial outcomes from 2 years' experience at the Oxford Cancer Centre, Oxford University Hospitals NHS Trust

Hill E. et al, (2015), LUNG CANCER, 87, S47 - S47

Single-cell dosimetry: effect of cell geometry on cellular S-values

Falzone N. et al, (2015), EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 42, S756 - S756

NTCP calculations for Selective Internal RadioTherapy (SIRT) - demonstration of the methodology

Abbott EM. et al, (2015), EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 42, S330 - S330

Effect of PI3K-Inhibition on Normal Lung Tissue Following Irradiation in a Murine Model

Eccles CL. et al, (2015), INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 93, E536 - E536

Imaging DNA damage allows detection of preneoplasia in the BALB-neuT model of breast cancer.

Cornelissen B. et al, (2014), J Nucl Med, 55, 2026 - 2031

Uptake, internalization and nuclear translocation of radioimmunotherapeutic agents.

Hillyar CRT. et al, (2014), Ther Deliv, 5, 319 - 335

Phase I trial to evaluate the tumor and normal tissue uptake, radiation dosimetry and safety of (111)In-DTPA-human epidermal growth factor in patients with metastatic EGFR-positive breast cancer.

Vallis KA. et al, (2014), Am J Nucl Med Mol Imaging, 4, 181 - 192

Targeting telomerase for the molecular radiotherapy of cancer

Jackson M. et al, (2014), JOURNAL OF NUCLEAR MEDICINE, 55

novel quantitative method in determining the spatial distribution of Auger electron-emitting radiopharmaceuticals used in targeted radiotherapy

Royle G. et al, (2014), JOURNAL OF NUCLEAR MEDICINE, 55

Targeting micrometastasis: A 3-D spheroid model to evaluate the efficacy of different targeting strategies

Falzone N. et al, (2014), JOURNAL OF NUCLEAR MEDICINE, 55

18F-labelled F3 derivatives for the PET Imaging of Tumour Angiogenesis via Cell Surface Nucleolin Receptor

Lam PYH. and Vallis KA., (2014), EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 41, S419 - S419

Can γH2AX be used to personalise cancer treatment?

Shah K. et al, (2013), Curr Mol Med, 13, 1591 - 1602

Characterization of single α-tracks by photoresist detection and AFM analysis-focus on biomedical science and technology.

Falzone N. et al, (2013), Phys Med Biol, 58, 7673 - 7682

Selective permeabilization of the blood-brain barrier at sites of metastasis.

Connell JJ. et al, (2013), J Natl Cancer Inst, 105, 1634 - 1643

Molecular radiotherapy using cleavable radioimmunoconjugates that target EGFR and γH2AX.

Cornelissen B. et al, (2013), Mol Cancer Ther, 12, 2472 - 2482

dvances in anticancer radiopharmaceuticals.

Jackson MR. et al, (2013), Clin Oncol (R Coll Radiol), 25, 604 - 609

dvances in anticancer radiopharmaceuticals

Jackson MR. et al, (2013), Clinical Oncology, 25, 604 - 609

Imaging DNA damage response (DDR) during oncogenesis

Cornelissen B. et al, (2013), CANCER RESEARCH, 73

Nanographene oxide-based radioimmunoconstructs for in vivo targeting and SPECT imaging of HER2-positive tumors.

Cornelissen B. et al, (2013), Biomaterials, 34, 1146 - 1154

Nano-graphene-oxide as a scaffold for molecular imaging

CORNELISSEN B. et al, (2013), Biomaterials, 34, 1146 - 1154

Imaging DNA damage response (DDR) during oncogenesis.

Cornelissen B. et al, (2013), CANCER RESEARCH, 73

TR targeting by the novel inhibitor VE-822 selectively sensitizes pancreatic cancer cells and tumors to radiation and chemoradiation

Fokas E. et al, (2013), STRAHLENTHERAPIE UND ONKOLOGIE, 189, 41 - 41

Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation.

Fokas E. et al, (2012), Cell Death Dis, 3

Photoresists as a high spatial resolution autoradiography substrate for quantitative mapping of intra- and sub-cellular distribution of Auger electron emitting radionuclides.

Falzone N. et al, (2012), Int J Radiat Biol, 88, 933 - 940

mplification of DNA damage by a γH2AX-targeted radiopharmaceutical.

Cornelissen B. et al, (2012), Nucl Med Biol, 39, 1142 - 1151

Clinical imaging of tumor angiogenesis.

Patel N. et al, (2012), Future Oncol, 8, 1443 - 1459

mplification of DNA damage by a γH2AX-targeted radiopharmaceutical

Cornelissen B. et al, (2012), Nuclear Medicine and Biology, 39, 1142 - 1151

Locoregional treatments for triple-negative breast cancer.

Eiermann W. and Vallis KA., (2012), Ann Oncol, 23 Suppl 6, vi30 - vi34

111In-BnDTPA-F3: An Auger electron-emitting radiotherapeutic agent that targets nucleolin

Cornelissen B. et al, (2012), Dermatology and Therapy, 2, 1 - 12

Relationship between chromatin structure and sensitivity to molecularly targeted auger electron radiation therapy.

Terry SYA. and Vallis KA., (2012), Int J Radiat Oncol Biol Phys, 83, 1298 - 1305

Relationship between chromatin structure and sensitivity to molecularly targeted auger electron radiation therapy

Terry SYA. and Vallis KA., (2012), International Journal of Radiation Oncology Biology Physics, 83, 1298 - 1305

111In-BnDTPA-F3: an Auger electron-emitting radiotherapeutic agent that targets nucleolin.

Cornelissen B. et al, (2012), EJNMMI Res, 2

111In-BnDTPA-F3: an Auger electron-emitting radiotherapeutic agent that targets nucleolin

Vallis KA. et al, (2012), EJINNM

Proteomic analyses reveal high expression of decorin and endoplasmin (HSP90B1) are associated with breast cancer metastasis and decreased survival.

Cawthorn TR. et al, (2012), PLoS One, 7

111In-BnDTPA-F3: An Auger electron-emitting radiotherapeutic agent that targets nucleolin

Cornelissen B. et al, (2012), EJNMMI Research, 2, 1 - 11

ger Emitting Radiopharmaceuticals for Cancer Therapy

Falzone N. et al, (2012), 461 - 490

Radiolabelled PEGylated nano-graphene oxide: Synthesis and SPECT imaging

Cornelissen B. et al, (2012), JOURNAL OF NUCLEAR MEDICINE, 53

Development of a Tat-conjugated anti-γH2AX Fab fragment SPECT probe to image DNA damage

Shah K. et al, (2012), JOURNAL OF NUCLEAR MEDICINE, 53

Dose-point kernels for Auger electron emitting radionuclides used in targeted radionuclide therapy

Falzone N. et al, (2012), JOURNAL OF NUCLEAR MEDICINE, 53

PERMEABILISATION OF THE BLOOD-BRAIN BARRIER AT SITES OF METASTASIS ENABLES TARGETED THERAPY DELIVERY

Connell J. et al, (2012), RADIOTHERAPY AND ONCOLOGY, 104, 24 - 24

Intracellular delivery of radioimmunoconjugates that target the cancer testis antigen, NY-ESO-1

Chu HL. et al, (2012), JOURNAL OF NUCLEAR MEDICINE, 53

Multimodality imaging demonstrates vessel-governed delivery of radiolabelled PEGylated nano-graphene oxide

Cornelissen B. et al, (2012), JOURNAL OF NUCLEAR MEDICINE, 53

Nano-graphene oxide as a scaffold for radioimmunoconjugates

Cornelissen B. et al, (2012), JOURNAL OF NUCLEAR MEDICINE, 53

ger electron-emitting radiopharmaceuticals targeting telomerase

Jackson M. et al, (2012), JOURNAL OF NUCLEAR MEDICINE, 53

DNA double-strand break imaging with anti-γH2AX antibodies does not alter DNA repair kinetics

Cornelissen B. et al, (2012), CANCER RESEARCH, 72

111-In-BnDTPA-bevacizumab for evaluation of response to antiangiogenic therapy

Patel N. et al, (2012), JOURNAL OF NUCLEAR MEDICINE, 53

Evaluation of different photoresists as quantitative, high spatial resolution autoradiography materials

Falzone N. et al, (2012), JOURNAL OF NUCLEAR MEDICINE, 53

Chemically amplified photoresist for high resolution autoradiography in targeted radiotherapy.

Falzone N. et al, (2011), Biomaterials, 32, 6138 - 6144

Imaging DNA damage in vivo using gammaH2AX-targeted immunoconjugates.

Cornelissen B. et al, (2011), Cancer Res, 71, 4539 - 4549

NCIC-CTG MA.20: An intergroup trial of regional nodal irradiation in early breast cancer.

Whelan TJ. et al, (2011), J Clin Oncol, 29

NCIC CTG MA.20: An intergroup trial of regional nodal irradiation in early breast cancer.

Whelan TJ. et al, (2011), J Clin Oncol, 29

ErbB-2 blockade and prenyltransferase inhibition alter epidermal growth factor and epidermal growth factor receptor trafficking and enhance (111)In-DTPA-hEGF Auger electron radiation therapy.

Cornelissen B. et al, (2011), J Nucl Med, 52, 776 - 783

Chemically amplified photoresist as a medium for quantitative 3-D high spatial resolution autoradiography

Falzone N. et al, (2011), JOURNAL OF NUCLEAR MEDICINE, 52

NCIC CTG MA.20: An intergroup trial of regional nodal irradiation in early breast cancer.

Whelan TJ. et al, (2011), JOURNAL OF CLINICAL ONCOLOGY, 29

NCIC-CTG MA. 20: An intergroup trial of regional nodal irradiation in early breast cancer

Whelan TJ. et al, (2011), JOURNAL OF CLINICAL ONCOLOGY, 29

Relationship between chromatin structure and sensitivity to molecularly-targeted radiation therapy

Terry SYA. and Vallis KA., (2011), CANCER RESEARCH, 71

ger electron therapy using 111In-labelled F3 peptide

Cornelissen B. et al, (2011), EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 38, S130 - S130

Potential advantages and tradeoffs of intensity modulated radiotherapy for locally advanced pancreas cancer (including elective nodal volumes)

Eccles CL. et al, (2011), STRAHLENTHERAPIE UND ONKOLOGIE, 187, 39 - 39

Comparison of contrast-reinforced lever Computed tomography (CECT) with FDG-PET-based Target volume definition in locally advanced Pancreatic Cancer (LAPC) for conventional and adaptive Radiochemotherapy (RCT)

Eccles CL. et al, (2011), STRAHLENTHERAPIE UND ONKOLOGIE, 187, 39 - 39

Comparison of Locally Advanced Pancreatic Cancer Target Definition Methods on 18FDG-PET images for Radiotherapy Treatment Planning

Eccles CL. et al, (2011), INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 81, S732 - S732

Tumour-specific delivery of cleavable radiolabelled antibodies against intranuclear γH2AX

Cornelissen B. et al, (2011), JOURNAL OF NUCLEAR MEDICINE, 52

POTENTIAL ADVANTAGES AND TRADEOFFS OF INTENSITY MODULATED RADIOTHERAPY FOR LOCALLY ADVANCED PANCREAS CANCER (INCLUDING ELECTIVE NODAL VOLUMES)

Eccles C. et al, (2011), RADIOTHERAPY AND ONCOLOGY, 99, S506 - S506

DEVELOPING BIOMARKER ASSAYS FOR DNA DOUBLE STRAND BREAKS

Shah K. et al, (2011), RADIOTHERAPY AND ONCOLOGY, 99, S321 - S321

Targeting the nucleus: an overview of Auger-electron radionuclide therapy.

Cornelissen B. and Vallis KA., (2010), Curr Drug Discov Technol, 7, 263 - 279

ntitumor effects and normal-tissue toxicity of 111In-nuclear localization sequence-trastuzumab in athymic mice bearing HER-positive human breast cancer xenografts.

Costantini DL. et al, (2010), J Nucl Med, 51, 1084 - 1091

Toenail selenium status and DNA repair capacity among female BRCA1 mutation carriers.

Kotsopoulos J. et al, (2010), Cancer Causes Control, 21, 679 - 687

Methotrexate, paclitaxel, and doxorubicin radiosensitize HER2-amplified human breast cancer cells to the Auger electron-emitting radiotherapeutic agent (111)In-NLS-trastuzumab.

Costantini DL. et al, (2010), J Nucl Med, 51, 477 - 483

In vivo monitoring of intranuclear p27(kip1) protein expression in breast cancer cells during trastuzumab (Herceptin) therapy.

Cornelissen B. et al, (2009), Nucl Med Biol, 36, 811 - 819

Computational analysis of the number, area and density of gamma-H2AX foci in breast cancer cells exposed to (111)In-DTPA-hEGF or gamma-rays using Image-J software.

Cai Z. et al, (2009), Int J Radiat Biol, 85, 262 - 271

Outcomes of surveillance mammography after treatment of primary breast cancer: a population-based case series.

Paszat L. et al, (2009), Breast Cancer Res Treat, 114, 169 - 178

Imaging of DNA double strand breaks in vivo using fluorophore-labelled TAT-immunoconjugates

Cornelissen B. et al, (2009), JOURNAL OF NUCLEAR MEDICINE, 50

The pharmacokinetics, normal tissue toxicity and anti-tumor effects of 111In-NLS-trastuzumab in mice bearing HER2-overexpressing breast cancer xenografst

Costantini D. et al, (2009), CANCER RESEARCH, 69

mplification of IR-induced DNA damage by Auger electron treatment with TAT-radioimmunoconjugates

Cornelissen B. et al, (2009), JOURNAL OF NUCLEAR MEDICINE, 50

Intracellular trafficking of 111In-DTPA-EGF is altered by co-administration of molecularly targeted anticancer agents and influences cell kill by Auger electrons

Cornelissen B. et al, (2009), JOURNAL OF NUCLEAR MEDICINE, 50

The pharmacokinetics, normal tissue toxicity and anti-tumor effects of [111]In-NLS-trastuzumab in mice bearing HER2-overexpressing breast cancer xenografts

Costantini D. et al, (2009), JOURNAL OF NUCLEAR MEDICINE, 50

Trastuzumab-resistant breast cancer cells remain sensitive to the auger electron-emitting radiotherapeutic agent 111In-NLS-trastuzumab and are radiosensitized by methotrexate.

Costantini DL. et al, (2008), J Nucl Med, 49, 1498 - 1505

Relationship between induction of phosphorylated H2AX and survival in breast cancer cells exposed to 111In-DTPA-hEGF.

Cai Z. et al, (2008), J Nucl Med, 49, 1353 - 1361

NANO PARTICLES IN RADIATION ONCOLOGY

Vallis KA., (2008), RADIOTHERAPY AND ONCOLOGY, 88, S19 - S19

phase I trial of 111In-human epidermal growth factor in patients with metastatic EGFR-positive breast cancer

Vallis KA. et al, (2008), INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 72, S178 - S179

Effect of the EGFR density of breast cancer cells on nuclear importation, in vitro cytotoxicity, and tumor and normal-tissue uptake of [111In]DTPA-hEGF.

Hu M. et al, (2007), Nucl Med Biol, 34, 887 - 896

Epidermal growth factor receptor inhibition modulates the nuclear localization and cytotoxicity of the Auger electron emitting radiopharmaceutical 111In-DTPA human epidermal growth factor.

Bailey KE. et al, (2007), J Nucl Med, 48, 1562 - 1570

(111)In-labeled trastuzumab (Herceptin) modified with nuclear localization sequences (NLS): an Auger electron-emitting radiotherapeutic agent for HER2/neu-amplified breast cancer.

Costantini DL. et al, (2007), J Nucl Med, 48, 1357 - 1368

Cone beam computed tomography guidance for setup of patients receiving accelerated partial breast irradiation.

White EA. et al, (2007), Int J Radiat Oncol Biol Phys, 68, 547 - 554

population-based case-cohort study of the risk of myocardial infarction following radiation therapy for breast cancer.

Paszat LF. et al, (2007), Radiother Oncol, 82, 294 - 300

123I-labeled HIV-1 tat peptide radioimmunoconjugates are imported into the nucleus of human breast cancer cells and functionally interact in vitro and in vivo with the cyclin-dependent kinase inhibitor, p21(WAF-1/Cip-1).

Hu M. et al, (2007), Eur J Nucl Med Mol Imaging, 34, 368 - 377

DNA repair capacity as a possible biomarker of breast cancer risk in female BRCA1 mutation carriers.

Kotsopoulos J. et al, (2007), Br J Cancer, 96, 118 - 125

Preclinical pharmacokinetic, biodistribution, toxicology, and dosimetry studies of 111In-DTPA-human epidermal growth factor: an auger electron-emitting radiotherapeutic agent for epidermal growth factor receptor-positive breast cancer.

Reilly RM. et al, (2006), J Nucl Med, 47, 1023 - 1031

What is the risk of cardiac morbidity with adjuvant radiotherapy for breast cancer?

Vallis K., (2006), Nat Clin Pract Oncol, 3, 180 - 181

Evaluation of 4dimensional-computed tomography for delineation of the clinical target volume (CTV) for breast boost radiotherapy.

Nageeti T. et al, (2006), RADIOTHERAPY AND ONCOLOGY, 81, S217 - S218

Evaluation of the inter- and intraobserver variability in tumour bed delineation for partial breast irradiation using CT and MR simulation images

Nageeti T. et al, (2006), RADIOTHERAPY AND ONCOLOGY, 80, S48 - S48

ccelerated partial breast irradiation using intensity modulated radiotherapy with more optimal beam arrangements

Cho J. et al, (2006), RADIOTHERAPY AND ONCOLOGY, 80, S15 - S16

Tat-immunoconjugates specifically inhibit the function of nuclear p21WAF-1/CIP-1 and differentially sensitize human breast cancer cells to antiproliferative agents

Hu M. et al, (2006), CANCER RESEARCH, 66

Cone-beam CT guidance for daily setup of patients receiving accelerated partial breast irradiation

White EA. et al, (2006), INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 66, S104 - S104

Evaluation of 4D computed tomography for planning boost radiation therapy in breast-conserving therapy

McGibney CA. et al, (2005), INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 63, S249 - S250

phase I clinical trial to evaluate the pharmacokinetics, toxicity and dosimetry of 111-indium-labeled human epidermal growth factor in patients with metastatic breast cancer

Vallis K. et al, (2005), RADIOTHERAPY AND ONCOLOGY, 76, S35 - S35

kit formulated under good manufacturing practices for labeling human epidermal growth factor with 111In for radiotherapeutic applications.

Reilly RM. et al, (2004), J Nucl Med, 45, 701 - 708

ntisense imaging of epidermal growth factor-induced p21(WAF-1/CIP-1) gene expression in MDA-MB-468 human breast cancer xenografts.

Wang J. et al, (2003), Eur J Nucl Med Mol Imaging, 30, 1273 - 1280

ntitumor effects and normal tissue toxicity of 111In-labeled epidermal growth factor administered to athymic mice bearing epidermal growth factor receptor-positive human breast cancer xenografts.

Chen P. et al, (2003), J Nucl Med, 44, 1469 - 1478

In regard to Rayan et al.: Prospective comparison of breast pain in patients participating in a randomized trial of breast-conserving surgery and tamoxifen with or without radiotherapy. IJROBP 2003;55:154-161.

Borok T., (2003), Int J Radiat Oncol Biol Phys, 56, 1508 - 1509

Prospective comparison of breast pain in patients participating in a randomized trial of breast-conserving surgery and tamoxifen with or without radiotherapy.

Rayan G. et al, (2003), Int J Radiat Oncol Biol Phys, 55, 154 - 161

In regard to Rayan et al.: Prospective comparison of breast pain in patients participating in a randomized trial of breast-conserving surgery and tamoxifen with or without radiotherapy. IJROBP 2003;55:154-161. Response

Vallis K., (2003), INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 56, 1509 - 1509

phase I study of 99mTc-hR3 (DiaCIM), a humanized immunoconjugate directed towards the epidermal growth factor receptor.

Vallis KA. et al, (2002), Nucl Med Commun, 23, 1155 - 1164

igh-throughput induction gene trap approach defines C4ST as a target of BMP signaling.

Klüppel M. et al, (2002), Mech Dev, 118, 77 - 89

Concurrent cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy and radiotherapy for breast carcinoma: a well tolerated adjuvant regimen.

Isaac N. et al, (2002), Cancer, 95, 696 - 703

Comparative antiproliferative effects of (111)In-DTPA-hEGF, chemotherapeutic agents and gamma-radiation on EGFR-positive breast cancer cells.

Chen P. et al, (2002), Nucl Med Biol, 29, 693 - 699

ssessment of coronary heart disease morbidity and mortality after radiation therapy for early breast cancer.

Vallis KA. et al, (2002), J Clin Oncol, 20, 1036 - 1042

Identification of radiation-responsive genes in vitro using a gene trap strategy predicts for modulation of expression by radiation in vivo.

Vallis KA. et al, (2002), Radiat Res, 157, 8 - 18

phase I study of 99mTc-h-R3 monoclonal antibody (DiaCIM ®), a humanized monoclonal antibody (mAB) for imaging EGFR-positive malignancies.

Reilly RM. et al, (2002), JOURNAL OF NUCLEAR MEDICINE, 43, 311P - 312P

ntisense imaging of epidermal growth factor (EGF) induced p21WAF-1/CIP-1 mRNA in MDA-MB-468 human breast cancer xenografts.

Wang J. et al, (2002), JOURNAL OF NUCLEAR MEDICINE, 43, 371P - 372P

mplified delivery of indium-111 to EGFR-positive human breast cancer cells.

Wang J. et al, (2001), Nucl Med Biol, 28, 895 - 902

The anti-tumor effect of the auger electron-emitting radiopharmaceutical, 111In-hEGF against MDA-MB-468 human breast cancer xenografts is tumor-size dependent.

Chen P. et al, (2001), JOURNAL OF NUCLEAR MEDICINE, 42, 255P - 255P

Expression trapping: identification of novel genes expressed in hematopoietic and endothelial lineages by gene trapping in ES cells.

Stanford WL. et al, (1998), Blood, 92, 4622 - 4631

Menadione-resistant Chinese hamster ovary cells have an increased capacity for glutathione synthesis.

Vallis KA. et al, (1997), Br J Cancer, 76, 870 - 877

Routine follow up of breast cancer in primary care. Study of open access centre for patients with breast cancer is planned.

Kirkbride P. and Vallis K., (1996), BMJ, 313

External beam and intraluminal radiotherapy for locally advanced bile duct cancer: role and tolerability.

Vallis KA. et al, (1996), Radiother Oncol, 41, 61 - 66

Relationship between the adaptive response to oxidants and stable menadione-resistance in Chinese hamster ovary cell lines.

Vallis KA. and Wolf CR., (1996), Carcinogenesis, 17, 649 - 654

Cookies on this website

Contact information

Research groups

Katherine Vallis

Research Summary

Biography

GROUP MEMBERS

Recent publications