Contact information
ester.hammond@oncology.ox.ac.uk
+44 (0)1865 617320
Follow the Hammond Lab on Bluesky - @Hammond-lab.bsky.social
Research groups
Research Theme
Tumour Microenvironment (Lead Principal Investigator)
Websites
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HIT-GLIO
HORIZON funded consortium
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RadNet seminar by Prof. Hammond
Watch on YouTube
Colleges
Ester Hammond
Professor of Molecular Cancer Biology
- TME Research Theme lead, Department of Oncology
- Academic lead for Department of Oncology Pathways to Academic Independence (PAI) programme
Research Summary
We investigate how tumours survive in conditions which include low oxygen (hypoxia). The goal is to target the hypoxic parts of tumours to improve cancer therapy.
Biography
Ester completed her PhD at the School for Cancer Sciences, University of Birmingham then accepted a post as a postdoctoral fellow within the Molecular Oncology Group at the University of Cambridge School of Clinical Medicine before moving to the USA to join the Department of Radiation Oncology at Stanford University, first as a postdoctoral fellow then a research associate. She joined the Department in 2007.
GROUP MEMBERS
Recent publications
PHGDH loss promotes hypoxia tolerance through glycolytic reprogramming and enhanced HIF-1 activity
Journal article
Petrosyan E. et al, (2026), Cell Death Discovery
HIF-1-regulated TPM3 links hypoxia to motility and invasion beyond the hypoxic fraction in triple-negative breast cancer.
Journal article
Zhou C. et al, (2026), NPJ Breast Cancer
Chromosomal instability shapes the tumor microenvironment of esophageal adenocarcinoma via a cGAS-chemokine-myeloid axis.
Journal article
Beernaert B. et al, (2026), Sci Adv, 12
Update Notice: Immunopeptidomics Workflow for Isolation and LC-MS/MS Analysis of MHC Class I-Bound Peptides Under Hypoxic Conditions
Journal article
Estephan H. et al, (2026), BIO-PROTOCOL, 16
High-Affinity Peptide-Drug Conjugate Ligands for the TRIM24 PHD and Bromodomain.
Journal article
Platt MA. et al, (2025), Chemistry, 31
Immunopeptidomics Workflow for Isolation and LC-MS/MS Analysis of MHC Class I-Bound Peptides Under Hypoxic Conditions.
Journal article
Estephan H. et al, (2025), Bio Protoc, 15

