Contact information
ester.hammond@oncology.ox.ac.uk
+44 (0)1865 617320
Follow the Hammond Lab on Bluesky - @Hammond-lab.bsky.social
Research groups
Research Theme
Tumour Microenvironment (Lead Principal Investigator)
Websites
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redOx⇌KCL
Collaborative interdisciplinary programme funded by the EPSRC
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RadNet seminar by Prof. Hammond
Watch on YouTube
Colleges
Ester Hammond
Professor of Molecular Cancer Biology
- TME Research Theme lead, Department of Oncology
- Director of the Oxford-MRC Doctoral Training Partnership
Research Summary
I investigate how tumours survive in conditions which include low oxygen (hypoxia). The goal is to target the hypoxic parts of tumours to improve cancer therapy.
Biography
Ester completed her PhD at the School for Cancer Sciences, University of Birmingham then accepted a post as a postdoctoral fellow within the Molecular Oncology Group at the University of Cambridge School of Clinical Medicine before moving to the USA to join the Department of Radiation Oncology at Stanford University, first as a postdoctoral fellow then a research associate. She joined the Department in 2007.
GROUP MEMBERS
RECENT GROUP ALUMNI & NEXT DESTINATIONS
Louise Martin (2023-2024) Research Assistant - DPhil student University of Oxford, UK
Çağla Tosun (2020-2024) DPhil student/Postdoctoral Researcher - Postdoctoral Researcher University of Nottingham, UK
Tiffany Ma (2018-23), DPhil student/Postdoctoral Researcher - Precision Immunomics Scientist Infinitopes, UK
Sam Bader (2016-21), DPhil student - Scientist, Totus Medicines, USA
Charlotte Simpson (2020-2021) MRes student - PhD student, University of Cambridge, UK
Natalie Ng, (2016–21), DPhil student - Scientist, Oxford Biomedica, UK
Anna Mandel, (2018-20), MRes student - PhD student, University of Toronto, Canada
Ania Skwarska, (2019-20) Postdoctoral Researcher - Postdoctoral Researcher Medical University of Bialystok, Poland
Elizabeth Bowler, (2019 -20) Postdoctoral Researcher - Postdoctoral Researcher University of Bath
Recent publications
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A guide to reactive oxygen species in tumour hypoxia: measurement and therapeutic implications
Journal article
HACKER L. et al, (2025), Molecular Oncology
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Reversible Enzymatic Switching of the Oxidation State of a EuIII/II Complex Controls Relaxivity.
Journal article
Sarson ET. et al, (2025), J Am Chem Soc
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Indolequinone-Based Hypoxia-Activated Proteolysis Targeting Chimeras Selectively Degrade BRD4 in Hypoxic Cancer Cells.
Journal article
Serafini M. et al, (2025), J Am Chem Soc, 147, 36352 - 36364
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Identification of a photoredox-active Pt(IV) complex that induces light-mediated cell death.
Journal article
Marsh JW. et al, (2025), Chem Sci
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Silencing of SOD1 sensitises ATRX-deficient cells to camptothecin treatment through increased activity of the alternative lengthening of telomeres pathway.
Journal article
Mattis N. et al, (2025), Hum Mol Genet
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UPR-induced intracellular C5aR1 promotes adaptation to the hypoxic tumour microenvironment.
Journal article
Suwa T. et al, (2025), Cell Death Dis, 16
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SRSF2 overexpression induces transcription-/replication-dependent DNA double-strand breaks and interferes with DNA repair pathways to promote lung tumor progression.
Journal article
Khalife M. et al, (2025), NAR Cancer, 7
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Chromosomal instability shapes the tumor microenvironment of esophageal adenocarcinoma via a cGAS-chemokine-myeloid axis.
Preprint
Beernaert B. et al, (2025)

