Contact information
Colleges
Undergraduate teaching
Dr Sevasti Zervou | St Peter's College Oxford
Biochemistry (Molecular and Cellular) | University of Oxford
https://www.spc.ox.ac.uk/undergraduate-courses/biochemistry
Sevasti Zervou
BSc(Hons) PhD FHEA
Director of Studies, MSc Precision Cancer Medicine
- Senior Teaching Fellow in Oncology
- Lecturer in Cellular Biochemistry, St Peter's College
- Member of Congregation
As the Director of Studies on MSc Precision Cancer Medicine, I look after all academic matters for our cohorts, module-lead 'Introduction to Human Genetics and Genomics' and coordinate Canvas content and teaching.
I obtained my PhD (Molecular Medicine) at the University of Warwick and then took up a Research Fellow position in Endocrinology and Diabetes until 2009. I then joined the Division of Cardiovascular Medicine in Oxford, as a Senior Researcher, funded by the British Heart Foundation (2009-2024).
My research expertise lies in the areas of Metabolism, Genetics, Cell Biology and I have extensive experience in cell-based assays, small molecule drug screening for target discovery, molecular phenotyping, protein post-translational modifications and -omics studies/analyses. I have worked in therapy areas covering cardiovascular science, diabetes, endocrinology, cancer.
Since 2021 I am a Stipendiary Lecturer in Cellular Biochemistry at St. Peter's College, Oxford, teaching Signalling, Metabolism, Cell structure and organisation, data handling to undergraduate students.
ORCID 0000-0002-4665-2747
Sevasti Zervou — University of Oxford, Medical Sciences Division
Sevasti Zervou BSc (Hons) PhD FHEA | LinkedIn
MSc in Precision Cancer Medicine — Department of Oncology (ox.ac.uk)
Recent publications
Hypercontractility and Oxidative Stress Drive Creatine Kinase Dysfunction in Hypertrophic Cardiomyopathy.
Journal article
Xu A. et al, (2025), Circulation, 152, 1705 - 1727
S-nitrosocysteamine-functionalised porous graphene oxide nanosheets as nitric oxide delivery vehicles for cardiovascular applications.
Journal article
Tabish TA. et al, (2024), Redox Biol, 72
Homoarginine and creatine deficiency do not exacerbate murine ischaemic heart failure.
Journal article
McAndrew DJ. et al, (2023), ESC Heart Fail, 10, 189 - 199
Influence of homoarginine on creatine accumulation and biosynthesis in the mouse.
Journal article
Lygate CA. et al, (2022), Front Nutr, 9
Subtle Role for Adenylate Kinase 1 in Maintaining Normal Basal Contractile Function and Metabolism in the Murine Heart.
Journal article
Zervou S. et al, (2021), Front Physiol, 12
Overexpression of mitochondrial creatine kinase preserves cardiac energetics without ameliorating murine chronic heart failure.
Journal article
Cao F. et al, (2020), Basic Res Cardiol, 115
SCREENING FOR SMALL MOLECULE REGULATORS OF THE CREATINE TRANSPORTER (SLC6A8)
Conference paper
Zervou S. et al, (2020), CARDIOVASCULAR DRUGS AND THERAPY, 34, 284 - 285
daptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism.
Journal article
Valli A. et al, (2019), Mol Cancer Res, 17, 1531 - 1544

