About Us

Oncology Clinical Trials Office

The Oncology Clinical Trials Office (OCTO) provides clinical trial management support to investigators across the CRUK Oxford Centre to manage trials from concept to completion.

Our trials portfolio can be viewed via links in the left hand sidebar.

OCTO was established in 2002 to run trials concerned with the practical application of high quality research into innovative and effective cancer therapies and prevention strategies. We aim to become the leading centre for translational early phase oncology trials in the UK.

We work with investigators to deliver trials in medical oncology, radiotherapy and imaging from first-in-human drug trials to large phase 3 clinical studies across a range of tumour types.  We have particular expertise in delivering early phase multi-centre trials for biologically distinct populations. By working with over 250 study sites (hospitals) and collaborating academic groups in the UK, Europe, USA and Australia we have recruited over 10,000 patients into trials.

We have established excellent relationships with academic groups, research communities, industry and patients to support the work of all our partner organisations:

• CRUK Oxford Centre
• NIHR Oxford Biomedical Research Centre (BRC) Cancer Theme
• Oxford Experimental Cancer Medicine Centre (ECMC)

We also work closely with colleagues in the state-of-the-art NHS Oxford Cancer and Haematology Centre to ensure that opportunities for collaborative research are maximised and that research is rapidly and efficiently translated into cutting-edge clinical treatment for cancer patients.

OCTO is the oncology division of the UKCRC registered Oxford Clinical Trials Research Unit (OCTRU) and a member of the NCRI Cancer CTUs Working Group.