Cultured human neural cells accumulate a heat-shock protein during acute herpes simplex virus infection
Kennedy PGE., LaThangue NB., Chan WL., Clements GB.
Herpes simplex virus-1 (HSV-1) infection of cultured human neural cells causes the accumulation of a host cell-encoded nuclear protein identified as a 57,000 mol.wt. stress protein by monoclonal antibody TI56. This protein is cell cycle-related in fibroblasts, may mediate host cell control during HSV infection and could play a role in the regulation of HSV latency. © 1985.