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Among 34 Epstein-Barr virus isolates from nonimmunocompromised Chinese donors, we identified three intertypic recombinants with type 1 sequences at the EBNA2 locus and type 2 sequences at some or all of the EBNA3A, -3B, and -3C loci. These appear to have arisen from independent, evolutionarily recent recombination events; such events may be commoner in nonimmunocompromised populations than hitherto imagined.

Type

Journal article

Journal

J Virol

Publication Date

02/2000

Volume

74

Pages

1544 - 1548

Keywords

Base Sequence, Blood Donors, China, Epstein-Barr Virus Infections, Epstein-Barr Virus Nuclear Antigens, Genotype, Herpesvirus 4, Human, Humans, Molecular Sequence Data, Polymerase Chain Reaction, Recombination, Genetic, Sequence Analysis, DNA, Viral Matrix Proteins, Viral Proteins