Robust breast composition measurement - Volpara™
Highnam R., Brady M., Yaffe MJ., Karssemeijer N., Harvey J.
Volumetric breast composition measurements generally require accurate imaging physics data. In this paper we describe a new method (Volpara™) that uses relative (as opposed to absolute) physics modeling together with additional information derived from the image to substantially reduce the dependence on imaging physics data. Results on 2,217 GE digital images, from a diversity of sites, show encouraging agreement with MRI data, as well as robustness to noise and errors in the imaging physics data. © 2010 Springer-Verlag.